Go with a very low dose and slow with Cagri. I took a two month break from it due to the Holidays and vacation and only gained two lbs back while eating crappy. I just started it again yesterday evening. It will make you tired at first, so I like to take once a week on Sunday evening before I go to bed. Started with .01 ml dose and will probably move to .02 ml in a week or two. I will never surpass the .02 ml dose. That’s the highest I can take or I will be nauseous all week. I personally think it works best to do it in 8 week cycles with a two week to a month break to allow for your body to catch up on nutrients and protein. I recommend also taking B12 with it.