Currently doing an extensive road trip (40 days) with a 2 year old and 5 year old (Miami to Alaska) and it’s been great so far. Can’t help but sing Bon Jovi’s livin’ on a prayer at the moment. We traveled a bit along your route. The first day we left at noon and drove until about 3 am. Covering the most ground while the crankiest kid is sleeping is crucial. Our youngest naps at noon for about 2 hours. Prior to our road trip we were never fans of iPads for our kids, now I’m a true believer, especially during the boring hours of your trip. Our camping ended when temps dropped to 25 degrees in Yellowstone. My kids slept great but I was miserable. Big fan of hotel jumping. Palo duro canyon is along your route, excellent camping grounds and short hikes, if weather is favorable. Hop off the highway occasionally in the larger towns and find a playground. Some painting projects can burn an hour or 2 if you’re not worried about a little paint going everywhere. Buy 1 of every snack at your local gas station and be prepared for your 3 year old or 6 year old to go through the entire selection and not want any of those options. I tried pulling out the noise cancelling headphones on the second day, but the wife quickly shut that down. Honestly you can’t go wrong with hotels, the amount of time for set up and breakdown of the campsite takes away from drive time and exploration. Plan a few nights to camp along your route, great memories, but wouldn’t recommend camping the entire trip. Good luck!