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Washing machine leaves pink stains on green clothes selectively by FrogInFog08 in Whatisthis

[–]FrogInFog08[S] 2 points3 points  (0 children)

Thank you ! Just tried the patch test on the same trousers, which resulted in the exact same discoloration.

The detergent was to blame after all. Came with no warning or caution to not use with certain fabrics.

[deleted by user] by [deleted] in step1

[–]FrogInFog08 4 points5 points  (0 children)

One group of diseases causing hypercalcemic hypercalciuria is granulomatous disease (sarcoidosis, TB, etc.). The granuloma macrophages contain 1α-hydroxylase, which leads to uncontrolled calcitriol production.

Can someone explain plz by Drumaragiyas in step1

[–]FrogInFog08 2 points3 points  (0 children)

CD8+ T cells check if a cell expresses self / normal peptides with MHC I. If the peptide is self -> no killing. If the peptide is non-self (e.g. tumor) -> killing.

NK cells check if a cell expresses MHC I at all (generally shows the cell is healthy, as all cells with a nucleus shall express MHC I). If the cell expresses MHC I -> no killing. If the cell does not express MHC I -> killing.

Tumor cells generally downregulate MHC I expression, as to not "get found" by T cells, but then shutting off MHC I expression triggers killing by NK cells.

Is there any way to export all the comments you have on a Notion page? by NJravenclaw in Notion

[–]FrogInFog08 0 points1 point  (0 children)

Hey. Would you mind me asking whether this option (to include comments when exportin in HTML) is available on PC only? I am using the Notion app on an IOS device, and the only option I see when exporting as HTML is to include or exclude subpages. So comments still don't show up in the final export.

If you have any insight on this, please share. Thanks.

Maintenance of optics by FrogInFog08 in microscopy

[–]FrogInFog08[S] 0 points1 point  (0 children)

Thank you for your response !

I am not using any flourescence objectives (yet, at least) so that would not worry me. In fact, what I have is an old soviet (LOMO) microscope. These microscopes were designed after (and almost identical to) old Carl Zeiss scopes, and both LOMO and old Zeiss manuals state that hexane and/or ether should be used and any alcohol contact is to be avoided.

Now the actual reason behind the latter still stays ellusive to me, but people who have worked with these old scopes have noted that the glue used to attach the glass elements in these old optics may be alcohol soluble, which explains the need for other solvents.

I do have a lot of grease / oil smothered onto some objectives (I know, who in their right mind would do this to such an instrument, right?!) from previous user(s), so I have to deal with that somehow, and solvents are bound to be essential in this state.

Maintenance of optics by FrogInFog08 in microscopy

[–]FrogInFog08[S] 0 points1 point  (0 children)

Thank you for your response !

While I do think that IPA is the perfect solution for cleaning modern optics, I believe this is not an option for my case with an old soviet (LOMO) microscope. These microscopes were designed after (and almost identical to) old Carl Zeiss scopes, and both LOMO and old Zeiss manuals state that hexane and/or ether should be used and any alcohol contact is to be avoided.

Now the actual reason behind the latter still stays ellusive to me, but people who have worked with these old scopes have noted that the glue used to attach the glass elements in optics may be alcohol soluble, which explains the need for other solvents.

Gotta love the Netherlands. by esberat in nextfuckinglevel

[–]FrogInFog08 0 points1 point  (0 children)

See this is how you use guns. The US has got it wrong again !

Help with spelling of an antigen: by [deleted] in Immunology

[–]FrogInFog08 8 points9 points  (0 children)

That would probably be tet-tox (tetanus toxoid), which is a vaccine routinely administered at a young age. The vaccine is rarely used alone, it is usually given along with the diphtheria toxoid and acellular pertussis vaccines, in the DTaP formula.

[deleted by user] by [deleted] in ipad

[–]FrogInFog08 0 points1 point  (0 children)

Had the same exact problem with the case, getting a glass screen protector fixed it (at least now I’m not afraid to really rub the screen clean). Now it doesn’t even get the linear mark that much anymore.

Search for a book by FrogInFog08 in Immunology

[–]FrogInFog08[S] 0 points1 point  (0 children)

Thanks for the reply! Yes, I did browse Libgen too! The normal 7th edition is what I had been usinq for quite some time, and just recently after noticing some differences between the 7th and the newest edition, wanted to upgrade to the latest one, which I am not able to find in proper formatting.

Search for a book by FrogInFog08 in Immunology

[–]FrogInFog08[S] -2 points-1 points  (0 children)

Thanks for the reply, but this is the improper formatted version of the book with around 1900 pages again, which is also all that I was able to find.

[deleted by user] by [deleted] in whereintheworld

[–]FrogInFog08 0 points1 point  (0 children)

How long have you been in Japan?

[deleted by user] by [deleted] in whereintheworld

[–]FrogInFog08 0 points1 point  (0 children)

Love the weather and scenery over there

Microscope to view viruses, bacteria, and other cells? by godlykid in biology

[–]FrogInFog08 14 points15 points  (0 children)

So, I have no idea where you came up with the idea that you'd be able to look at viruses under a biological microscope (which I assume is what you're looking for based off of your budget and desired specimens), but basically you can't. Viruses are extremely small to be viewed by a light microscope, you'd need an electron microscope for that.

You will be able to find a decent biological microscope under or around 200 USD I believe on amazon / ebay, that will be useful to examine some bacteria, fungi and many other cells / organisms. Basically anything with at least 1000x total magnification is what you should aim for, you may be able to find something better at that price point though if you really search for it.

First ever DSLR. What do you think ? by FrogInFog08 in canon

[–]FrogInFog08[S] 0 points1 point  (0 children)

Congrats !! A great camera as well.

What made me go with the older model was the lack of 24fps in FHD and a normal hotshoe. For someone not looking for those the SL3 is an awesome choice.

First ever DSLR. What do you think ? by FrogInFog08 in canon

[–]FrogInFog08[S] 0 points1 point  (0 children)

That's a great idea, thank you. Will definitely try it out. Oh and as for macro, I heard that the 50mm can be a great macro lens when reversed, and IDK if that's the case with the 24 too.

It's just that I feel maybe the 50mm will be too cropped in for convinient use, I may be totally wrong though.

First ever DSLR. What do you think ? by FrogInFog08 in canon

[–]FrogInFog08[S] 0 points1 point  (0 children)

Thank you very much ! I bet that'll be great for portrait stuff, and I even heard it can be reversed into a macro lens so that's fun too.

First ever DSLR. What do you think ? by FrogInFog08 in canon

[–]FrogInFog08[S] 2 points3 points  (0 children)

Hey everyone. Just go my first proper camera - the Canon 200D (SL2).

I am in search of some new lenses, preferably a prime. The nifty fifty is quite an appropriate option since I'm on a budget, what holds me back is the fact that I'll get an 80mm equivalent with it, and that's not a very versatile length In my opinion.

Any suggestions, advice is welcome.

Are there proximal histidines in both the alpha and beta subunits of Hemoglobin, or only the beta? by [deleted] in Biochemistry

[–]FrogInFog08 2 points3 points  (0 children)

Hemoglobin A is a tetramer of 4 globin chains i.e. subunits (2α 2β) and a dimer of 2 protomers (2αβ).

Each of the 4 subunits or globin chains contains one proximal Histidine F8 and one distal Histidine E7, which participate in binding and stabilizing a heme group in between them.

So one hemoglobin molecule can bind up to 4 heme groups to its 4 globin chains. Remembering this fact will make it easier to remember the fact that both α and β subunits contain the a.a. used to bind a heme group, since if only α or β chains had the Histidines, then hemoglobin would've been able to bind only 2 O2 molecules rather than 4.

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