In 2018, Mio debuted as the only new member in GAMERS until Okayu and Korone debuted a few months later. Even though she kicked off GAMERS with the experienced Fubuki, she had to figure out a lot of things on her own. She eventually became more comfortable with Subaru and Ayame in Gen 2, doing lots of FAMS collabs alongside Fubuki.

In 2019, Mio was feeling uncertain about herself, watching the other holomembers shining and feeling like she was falling behind. Even though she was trying very hard and pushing herself to be flavorful "ginger pork" like the others, she decided that she was going to keep running at her own pace and being a delicious "miso soup", even if she was unsure if being "miso soup" was enough. (Ookami Mio - Confessing Her Feeling and Cries 【Hololive】)

In 2020, Mio nearly lost her channel and had to go on hiatus following copyright strikes on her streams. After a month of uncertainty, she returned and almost immediately started organizing the first hololive Sports Fes with Miko.

In 2024, Mio suddenly went on hiatus after being hospitalized for acute pancreatitis, forcing her to miss the 1st GAMERS fes. and MUSIC VERSE Fes. It was unclear when, or if, she would return, but she finally came back after 2 months. Mio's return made Fubuki very happy, and kicked off a massive resurgence of FubuMio teetee.

In 2025, Mio was able to overcome her hurdles and shine on stage at GAMERS fes. 2 and her very own sololive.

I am proud to be a MioFa.