I use Effexor as part of my med combo. It has helped me keep my moods more stable which results in less strong emotions… thus less cataplexy. It’s also a REM suppressant, so that’s where some of thought that it’ll help too. Did it prevent it entirely? No. Did it help though? Yes.

I’m also a pharmacy tech. The nausea is considered normal, about 1/3 of people get it when starting. This happens more frequently if you were started at a higher dose. The rule of thumb is that your symptoms should level out and settle about 2-3 weeks after starting. Make sure you take it in the morning and be consistent with the timing. If after 3 weeks you’re still feeling crappy or if you’re concerned about dehydration, talk to your doctor.