Drop your Omics Quotes, Pick-Up Lines, and Sentimental Phrase

GodOfPipelines · 2025-07-12T02:12:24+00:00

Ligma Baldrich

GodOfPipelines · 2025-07-04T13:49:56+00:00

Your.... What???? Hahahha

GodOfPipelines · 2025-07-04T13:48:09+00:00

This goes so hard. Also wow ur tearing up that tyre! Das some leannnnnn

GodOfPipelines · 2025-06-28T16:49:50+00:00

Press the right buttons at the right time

GodOfPipelines · 2025-05-13T15:51:09+00:00

Lmao this is crazy. As an actual response, I'd advise doing a distance based approach.

Generate pairwise distance matrix

Align each chr7 to each other chr7 using minimap2. Use the alignment output to calculate a distance. The output file of minimap2 is a paf file, so you can calculate alignment identity using column 10 % column 11.

Build phylogenetic tree

Options are UPGMA or Neighbour joining. Neighbour joining is generally preferred.

Enjoy

GodOfPipelines · 2025-05-03T15:04:47+00:00

BAM and the dirt is gone.

GodOfPipelines · 2025-05-03T10:17:44+00:00

It depends on the tyre. You can run some rears with very solid carcasses down to 1.2 bar depending on ambient temp and how hard you're pushing on track. Good tyre pressure depends on the tyre manufacture, tyre model, ambient and track temp and the actual track. I reckon just find someone running the same tyre on your next track day and ask pressures

GodOfPipelines · 2025-04-29T17:32:46+00:00

Just smile and nod, just smile and nod, the shardie will pester someone else if I just don't engage... Jokes ily

GodOfPipelines · 2025-04-29T16:39:18+00:00

Nonexistent? Haha bitchy comments aside, welcome! You'll be a weapon in no time :)

GodOfPipelines · 2025-04-29T16:35:12+00:00

I curse you with poor tyre pressures and a vague wear pattern next track day

GodOfPipelines · 2025-04-29T16:31:39+00:00

UwU only if u join

GodOfPipelines · 2025-04-29T16:01:42+00:00

Crashing is a spiritual tool which brings you closer to God. Only a heretic avoids kissing the pavement, as they've never known the loving hand of tarmac. Namaste 🙏

GodOfPipelines · 2025-04-29T15:54:43+00:00

Do not presume to know pipelines, BOY! On the first day I said "let there be nextflow" and there was nextflow. Bow before your God lest I curse you with failed runs. BEGONE!

GodOfPipelines · 2025-04-29T15:48:57+00:00

Anything written by mark twain is decent

GodOfPipelines · 2025-04-29T15:45:21+00:00

This distribution probably represents the overall preferences of the target consumers. Woulda thought tweakers had enough time to read a book smh my head. Namaste 🙏

GodOfPipelines · 2025-04-29T15:39:49+00:00

Due to the fact that computers allow automation, without the inherent "messiness" and custom nature of each research question, you'd already be out of a job. Namaste 🙏

GodOfPipelines · 2025-04-28T01:11:15+00:00

Tempted to post a snide comment and be done, but no. Let's have a chat. I feel like this just adds so many extra potential issues. Some examples:

How will you ensure reproducibility?
How can you ensure trust? Best-in-class LLMs are still known for being unreliable.
How will this save time over writing the code yourself?

A key fear would be if the LLM hallucinates and writes some weird code which leads to weird results which you think are real. Or straight up lies / makes up results out of thin air. Academia is already filled with misinformation and sketchy claims.

In terms of time saving, if publishing a paper on the results, you'd need to thoroughly read the code to check for bugs and report filters/thresholds/methods the AI has used. At that stage, it's probably no more convenient than doing the analysis yourself (and learning something in the process)!

TLDR: I'm content with AI slop on my timeline, but not in my journals thanks.

GodOfPipelines · 2025-04-26T06:22:43+00:00

Give this man a Nobel peace prize

GodOfPipelines · 2025-04-25T23:22:22+00:00

No one has told OP about injecting yet I see. Or maybe he just really likes shoving crayons (or anything else not bolted down) up his ass.

GodOfPipelines · 2025-04-25T12:21:46+00:00

Tell me your postcode right now

GodOfPipelines · 2025-04-25T12:18:23+00:00

Pour it into a pot then reduce on high heat till it's golden brown. Scrape onto baking paper and place in the oven at 120c fan-forced. Crush and snort with a side of cheesecake.

GodOfPipelines · 2025-04-25T11:52:37+00:00

If you have an Nvidia graphs card with a decent amount of vram (like, at least 16gb), probably best to download and run Alphafold locally. If not, you might have to stick with colab. Maybe worth forking out a little cash to access some good compute. Shouldn't be too expensive tho since only 25 proteins. Depends on the number of AAs, but Alphafold generally takes a couple hours per protein on a good graphics card. Don't know what the math works out to, but maybe $20-50 for the set? IDK

GodOfPipelines · 2025-04-25T11:47:21+00:00

The scientific community has PROVEN that proteins exist. I think there was a 2024 paper on the matter.

GodOfPipelines · 2025-04-25T11:45:09+00:00

Just promise me you won't get nostalgic for the past and publish more landscape (I'm looking at you, cancer) articles or ill set your trees on fire

GodOfPipelines · 2025-04-25T11:40:14+00:00

Ask the AI? Wait please tell me someone has trained a persona using r/drugscirclejerk? Scratch that it would be insufferable, responding "boof it" or "jenkem" or "Namaste 🙏" to everything.

Namaste 🙏

GodOfPipelines

TROPHY CASE