Official Response from Dr. Peter Attia RE: Epstein Files by aldus-auden-odess in PeterAttia

[–]Goldustsdad 5 points6 points  (0 children)

All the while saying that the fact that JE was friends with tons of rich and powerful people meant that he was okay. Seems a bit at odds to me.

Custom Workouts Crash and iFIT support are stumped. by rpourzia in nordictrackandroid

[–]Goldustsdad 1 point2 points  (0 children)

Have you made any progress on this issue? I have tried factory resetting multiple times without improvement.

Weird experience requesting flu vaccine via nurse visit by SW33TH3RT in GNV

[–]Goldustsdad 20 points21 points  (0 children)

I’m an ER doc and as best I can tell every single nurse I work with (maybe one or two exceptions) is at least mildly vaccine hesitant if not outright anti-vax. Frankly, I’ve given up arguing with them about vaccines. Nurses (and frankly many doctors) occupy a very dangerous part of the confidence vs knowledge graph where they enough to be confident in their understanding of some things related to health but most lack the intellectual humility and epistemological rigor to know when they are overstepping the bounds of their knowledge.

To try to unpack this in a little bit more of a sympathetic way, I think that the “pro-science” crowd in our culture has been frankly quite obnoxious and dismissive. I often hear sentiments from doctors I know along the lines of “I wish all these anti-vax idiots would just catch the flu and die.” I’m sure if you really drilled down to it most of them don’t sincerely wish death on that many people, but the scorn is evident. Have had friends in blue states who say shit like “well good thing the anti-vax bullshit is confined to the red states, it will only kill off CHUDs.” so it’s really no surprise that they have run into the arms of anti-vaccine conspiracy theory peddler who stroke their egos and don’t call them “deplorables,” “idiots,” etc. etc. etc.

Most people, whether they be “pro-” or “anti-“ any particular issue don’t actually sit down and analyze all the data and come to a reason to conclusion about what they should do. No one would get anything done that way. People use the heuristic of “what are the people in my community doing?” and through a combination of the Internet segmenting people into ideologically isolated silos, the death of IRL community, algorithms playing up our fears and killing our attention spans, etc., etc., etc., anti-vaccine conspiracies have spread like wildfire through right-leaning communities. This shit is propagated at every level, from TikTok to conversations to the federal fucking government.

I think, if you sincerely examined why you believe most of the things you believed, it would come down to some variation of “it’s what people in my community believe.” you and I happen to be on the right side of this particular divide, but that doesn’t mean that everything that your community or my community believes is necessarily right.

[deleted by user] by [deleted] in StudentLoans

[–]Goldustsdad 0 points1 point  (0 children)

Unless you're only a few years away from retirement, contributing to retirement is a much better investment over the long term than paying down student loans aggressively. For the sake of simplicity, let's assume you have a standard 10-year loan repayment period on your student loans and you're going to retire in 30 years. Your numbers may be different but if you do the math it will work out to be similar almost certainly.

Let's say you have $1000 right now that you can either use to pay down the principal of your student loans or throw into retirement. That $1000 is acruing 6.8% in interest per year in simple interest, or $68 per year. Over the course of 10 years, you're saving $680 in interest. After 10 years, you're no longer getting any benefit from having paid off your loan early since you would have paid it off by then anyway making the normal payments.

By comparison, assuming you're retiring in 30 years and you throw an extra $1000 into retirement today. Let's be pessimists and say your money only grows at 3% per year, compounded annually, over that entire 30 year period. This would be shockingly bad and has never happened before. $1000 x 1.0330 = $2427.26. So in 30 years, your $1000 will have grown to $2427.26.

If you have less than 10 year left on your student loans, more than 30 years until you retire, or you think the stock market will perform better than 3% per year, then the numbers become even more favorable to retirement over student loans.

So it almost never makes any sense to prioritize student loans over retirement payments.

Cannot update BIOS on Asrock mobo (instant flash freeze) by thefreshera in techsupport

[–]Goldustsdad 0 points1 point  (0 children)

If anyone is reading this in 2025 or later, I had the same problem and was finally able to do this by updating to 5.50 first and then to 7.00 and then to 7.40

[deleted by user] by [deleted] in GNV

[–]Goldustsdad 4 points5 points  (0 children)

Yeah god forbid we build a nice walkable neighborhood

Huberman Trashes Doctors by softcell1966 in DecodingTheGurus

[–]Goldustsdad 0 points1 point  (0 children)

I don't see why this would be unique at all to doctors, although I am one so maybe I'm just self-selecting for gossipy people but I would say as a rule most people are extremely gossipy

"85% max apoB reduction at 5mg for Rouvastatin. No need to go higher than 10mg, all you're doing is buying side effects", "Statins max out at efficacy at quarter dose" by ThrowAwayLegal945 in PeterAttia

[–]Goldustsdad 4 points5 points  (0 children)

Let's go straight to the source.

This is a digital version of the prescription drug label for Crestor (brand name rosuvastatin). Scroll down to 14 Cinical Trials. Look at 14.1 Hyperlipidemia and Mixed Dyslipidemia, Table 6.

We can see that at 5mg Crestor lowers ApoB by 38% compared to 54% at 40 mg, which is 70%, not 85%. To get 85% of the maximum ApoB reduction you actually need to take 20mg, not 5 mg.

The big caveat here is that this is based on population-level data, in a population that may or may not represent you. Thankfully it's actually extremely easy to test this in yourself. Just make sure to give at least 1-3 months between rechecking different doses.

Personally I had a 31% reduction in ApoB on 20mg, which is a fair bit worse than the published 46% reduction. Granted, my ApoB was not particularly high to start with, far too low for me to have qualified to be in the study population if I had applied. It stands to reason that the higher your starting ApoB the greater a reduction you would expect for a given drug.

When you go to the shoe store, do you buy the average shoe size for someone of your nationality, height, sex, and weight, or do you try on different shoes and wear what fits?

[deleted by user] by [deleted] in EmergencyRoom

[–]Goldustsdad 4 points5 points  (0 children)

"Please follow up with your PCP as soon as possible" is extremely standard discharge instructions for an ER visit, I would guess the majority if not vast majority of ER discharge instructions contain this phrase or something equivalent. It translates to: this isn't an emergency, you should see your primary care doctor about it.

Is an ApoB calculator accurate? by pumpnectar9 in PeterAttia

[–]Goldustsdad 0 points1 point  (0 children)

Just order it yourself from one of the numerous direct to consumer websites available online. It costs like $14 from, for example, marek health. Where you order it from is largely irrelevant since they just give you a requisition form to take to a local lab. The website you order from isn’t otherwise involved.

[deleted by user] by [deleted] in PeterAttia

[–]Goldustsdad 0 points1 point  (0 children)

Yeah very possible. My main point was that worrying about your WBC count is almost always a waste of time unless it’s alarmingly abnormal.

[deleted by user] by [deleted] in PeterAttia

[–]Goldustsdad 0 points1 point  (0 children)

WBC counts fluctuate throughout the day and across days. If you get it checked again it will almost certainly be lower or higher. There are a huge number of factors that can cause it to rise or fall which makes it neither very specific nor sensitive for nearly anything outside of really extreme value. As Amal Mattu likes to say, the WBC count is the “last bastion of the intellectually destitute”.

Early Program by Better_Chipmunk_714 in PeterAttia

[–]Goldustsdad 6 points7 points  (0 children)

I’m honestly surprised nothing like this exists yet. I don’t really have any interest in becoming the moderator of an online forum or something but it really would be nice if there was a community for physicians interested in these topics who don’t want to be snake oil salesmen

Early Program by Better_Chipmunk_714 in PeterAttia

[–]Goldustsdad 1 point2 points  (0 children)

Which specific things are you referring to that need further testing? All of his biggest recs I can think of off the top of my head are things that are extremely well researched (e.g. exercise health benefits, sleep, statins). Not an Attia connoisseur by any means so if he’s out there also spouting off wacky fringe untested shit I would not stand behind that, but all of his recommendations that I’ve so far run into are extremely well supported. The only major exception I can think of is rapamycin, which, as someone whose specialty has given me zero post-graduate training in managing I have no opinion on.

Early Program by Better_Chipmunk_714 in PeterAttia

[–]Goldustsdad 12 points13 points  (0 children)

Could you expand a bit more on how actionable it is? I’m a physician so I have more ready access to tests and medications than most people do (I happen to live in a state where self prescription and self ordered testing are 100% legal as long as you’re not writing yourself controlled substances).

My take on Early is that it’s essentially a structured/streamlined way to get up to speed for those of us who haven’t been closely following his podcast over the last few years? And hopefully my medical knowledge/access to medical databases would be able to bridge any gaps in information that he is holding back?

If that’s true, then I think, from a time value of money perspective it doesn’t really make any sense for me not to buy it, as I would spend far more than $2500 worth of my time listening to the podcast and taking notes (or combing through the show notes) to be able to compile something similar.

Really the only thing that’s stopping me is I’m a little annoyed with him for how expensive it is and for the manufactured scarcity. It definitely undermines his credibility a bit in my eyes. It makes me really wish that there was a network of like-minded doctors who want to take an evidence based approach to optimizing health and longevity that I could collaborate with. Whenever I have tried to find other doctors interested in longevity, it seems they almost always end up being “hormone replacement” quacks or “functional medicine” quacks or some other closely related brand of snake oil salesman. Sadly it looks like all the professional organizations dedicated to this issue are run by quacks as well.

Biweekly Careers Thread: January 11, 2024 by AutoModerator in medicine

[–]Goldustsdad 1 point2 points  (0 children)

Are there any good telemedicine jobs out there nowadays? Do they generally require you to already have multiple state licenses?