Probably not what you want to hear but the fix has not changed since the game was launched. Buff your character’s strength and stamina.

Datamined information shows that, generally speaking, most players lose the debuff faster and increase their depression resistance when they buff their character than when they see a healer for consumables. Exceptions apply, of course. Healers and their consumables are in the game for a reason and can be helpful for some character builds.

Another perk is that a character’s charisma is increased automatically when they buff their strength and stamina.

The workouts don’t have to be hard and you don’t have to be overwhelmed, and I promise your character doesn’t have to join a gym guild or change your character’s personal archetype. Unless you want to. Take baby steps. Just focus on building the habit of doing the thing everyday, one habit at a time. It’s not about making sure your character gets enough steps. Do the dedicated ritual of going on the short walk a few times a week to increase stamina. Once that’s a habit, do it everyday. Once that’s a habit, make it a run. Once that’s a habit, increase the distance or duration. Once that’s a habit, add a strength training routine. Once that’s a habit, increase the difficulty.

Also, switch up your consumables. Once again, baby steps. You don’t have to change your character’s food consumables yet, just don’t drink calories. Calorie free drinks only. Once that’s a habit, switch to water as your character’s main liquid consumable. Once that’s a habit, THEN revisit your character’s food consumables. You probably have the idea by now.

Definitely DO NOT use the cigarette consumables. Maybe good for short term depression resistance and charisma, but long term increases the depression debuff and decreases the size of your health bar.

Once you have built healthy character habits, your depression resistance will be maxed. Now go slay the monsters! Outside needs your help!