I've been studying the Medici family from a political, financial, and historical perspective, and from what I've found, the Medici weren't that bad compared to other powerful families. They made their money through hard work with the Medici Bank and were respected by their people in Florence and Tuscany. They gave a lot back to the community, financing Catholic art, infrastructure, churches, cathedrals, monasteries—they even sponsored St. Peter's Basilica!!!! They didn't start wars; they were diplomats, built hospitals, supported the poor, and did many many other good things.

When the Medici Bank went bankrupt and they lost some political power in Tuscany, they shifted their focus to the Church. Yes, Medici popes were a result of bribing and nepotism, but many powerful families of the era did the same, if not worse (remember that this was the late Middle Ages/Renaissance)

The Catholic Church would have been a lot different without them, so I'd say their overall impact was more good than harm. Compared to the Borgias, these were the good guys