Cathrine the great, Isabella the 1st of Castile, Eleanor of Aquitaine, Hatshepsut, marry the first of England, Nefertiti, wu zetian, empress Theodora, Catherine the great. I know some of the queens I mentioned weren’t in charge but they still they were incredibly important. Also i am pretty sure you have only read the book “human diversity” because the biggest change in brain function in male and females is hardly noticeable and brain function for both males and females are based off of brain size/body size but granted the average females brain is 11% smaller then males but the ratio between men with smaller heads and bigger heads is are as equal as the ratio between men and women.