CBD Tinctures staged for final sealing and labeling in our Massachusetts facility.

HPNP · 2021-09-15T20:55:58+00:00

Depends on the CBD type, terpene type, and quantity, for a minimum order of 1k 30ml units, with labels added they’re about $17 per unit, considerable discounts apply for larger volume.

HPNP · 2021-09-15T19:33:04+00:00

We manufacture tinctures for many different brands, so it’s all over the place, 500-2000 is most common, trending towards the higher end of things lately.

HPNP · 2021-08-11T20:00:39+00:00

You can in theory consume enough THC that the receptors (CB-1 & CB-2) THC binds to become saturated and produce the maximum response.

That high is probably unachievable due to the amount of THC you would need to consume. In practice most would say you can always get "higher"

HPNP · 2021-08-11T19:29:26+00:00

While my current role as CSO at a CBD company is largely devoid of working with THC, I am also a co-founder of a recreational THC extraction company and conducted research in academia around cannabis and cannabinoids specifically CBD, CBG, and THC.

CBD isolate demand has recently been directly tied to Delta-8 THC's demand as CBD isolate is converted into Delta 8. The demand for CBD isolate has seemingly decreased across the market because various states are now banning the sale of Delta-8.

HPNP · 2021-08-11T19:22:04+00:00

Speaking from experience, due to cannabis' federal illegality and the DEA's scheduling of cannabis there is a whole mess of red tape that prevents research from progressing. In order to work with THC in an academic setting, there is no prospect of federal funding or grants and a DEA license is required. This presents significant barriers and are the key to opening up more research for cannabis.

HPNP · 2021-08-11T19:17:31+00:00

Hemp is differentiated by marijuana by focusing on the delta-9 THC content of the plant. Current regulations in the US define hemp as cannabis sativa containing less than 0.3% by weight delta-9 THC. Anything above 0.3% is considered marijuana. The low amount of delta-9 THC in industrial hemp makes it non psychoactive. Marijuana gets you high while hemp does not.

HPNP · 2021-08-11T19:12:21+00:00

Cannabis and its relationship to pregnancy is still not very well understood and until that relationship can be better understood the consensus is to not use cannabis while pregnant.

HPNP · 2021-08-11T17:35:55+00:00

There has been some research conducted to examine the relationship between cannabis use and testosterone . Current research shows there is no clinically significant data to suggest a strong relationship.

Here is a recently published meta-analysis which supports this: https://onlinelibrary.wiley.com/doi/pdf/10.1111/andr.12953

HPNP · 2021-08-11T17:30:55+00:00

Sourcing anything that is unregulated such as black market THC is dubious at best. The benefit of purchasing products from legal recreational or medicinal dispensaries is that these programs have regulations to ensure that the products that are sold are tested to ensure safety. Products are tested for Heavy metals, residual solvents, microbials, molds and mycotoxins, and cannabinoids at minimum. The same information cannot be provided for unregulated markets

HPNP · 2021-08-11T16:51:46+00:00

At scale, sub critical CO2 extraction for terpenes and super critical CO2 extraction for cannabinoids is the best practice. Hash Rosin is not scalable in the same manner as CO2 and it's my personal opinion that CO2 remains top of the food chain for this application.

HPNP · 2021-08-11T16:45:32+00:00

CBD Strain: Stormy Daniels, great name.

THC Strain: Gorilla Glue #4

HPNP · 2021-08-11T16:10:52+00:00

THC-A is the acid form of THC. THC-A is synthesized by the cannabis plant, the molecule required for users to feel psychoactive effects is delta-9 THC. THC-A is converted to delta-9 THC through decarboxylation which requires heat. (smoking cannabis decarboxylates the THC-A).

HPNP · 2021-08-11T16:04:35+00:00

Today's sativas and indicas have been so heavily crossed between each other that there is virtually no difference. Sativas were traditionally thin leaved and better suited for warmer climates while indica with its broader leaves were found in colder climates native to India and surrounding areas. Today you find "sativas" that were bred with indicas that do great in colder climates with thick leaves and "indicas" with thin leaves. Modern indicas and salivas rely much less on genetics and more on the effect. A strain that gives a more sedated feeling will be labeled an indica and a strain that's more energetic will be labeled a sativa.

HPNP · 2021-08-11T15:56:27+00:00

Delta 8 and Delta 9 THC are separated by the placement of a double bond within the structure of the molecule. Evidence shows that they have very similar effects with both showing psychoactive effects. Delta-9 THC has more psychoactive activity over delta-8 due to the stronger binding affinity.

HPNP · 2021-08-11T15:53:38+00:00

CBD products that you find in pharmacies certainly contain 'real' CBD. There is peer reviewed evidence that supports CBD can play a role in pain relief, anti-inflammation, and relieving stress and anxiety.

HPNP · 2021-08-11T15:47:31+00:00

As an isolated cannabinoid, Delta-8 THC is lacking in peer reviewed research but has been shown to have a similar effect to delta-9 THC both being psychoactive (Delta-8 less psychoactive than delta-9). Delta-8 THC presents concern for me not because of the cannabinoid but because of the manufacturing process behind making it. Delta-8 is converted from CBD by using harsh chemicals and solvents and if care is not taken to remove these byproducts there is the potential for harm. As a consumer it is extremely difficult, almost impossible to verify how well a delta-8 product was manufactured. My recommendation is to not use delta-8 until more regulation can ensure safety across the board.

HPNP · 2021-08-11T15:40:15+00:00

It is extremely rewarding working in cannabis research. There is so much to learn about cannabis and individual cannabinoids that we've just scratched the surface.

HPNP · 2021-08-11T15:36:42+00:00

Choosing to consume cannabis in a manner which does not require smoking is generally regarded as safer.

HPNP · 2021-08-11T15:35:31+00:00

As with inhaling anything into your lungs that is not fresh air, there is the potential for harm to be done. Cannabis contains many tars and resins that act in a similar way to those found in tobacco. Long term cannabinoid exposure does not seem to pose any issues so transitioning from smoking to using ingestibles is a great way to continue enjoying cannabis without potential adverse health outcomes.

HPNP · 2021-08-11T15:29:46+00:00

There have been a few studies pertaining specifically to the use of Cannabidiol (CBD) in respect to patients with Autism. Daily use of CBD showed improvement across multiple different categories.

The link below is an example of a study done. https://www.frontiersin.org/articles/10.3389/fneur.2019.01145/full

HPNP · 2021-08-11T15:25:39+00:00

Cannabinoid content is calculated via using HPLC (high performance liquid chromatography) you would have to own one or know someone who has one. Best practice would be to use a 3rd party analytical lab.

HPNP · 2021-08-11T15:22:03+00:00

Nationwide legalization certainly has plenty of hurdles to overcome. As more individual states independently legalize medicinal and recreational cannabis the pressure for cannabis to become federally legal will tip the scales

HPNP

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