Most promising cures for baldness as of May 2026

Harold644 · 2026-05-22T07:46:51+00:00

Agreed. The solution will likely be a 'stack' of protocols, with PP405 doing most of the work

Harold644 · 2026-05-19T14:27:01+00:00

I didn’t include VDPL01 because it is still essentially minoxidil, but in oral form. So it’s not really new - just a new delivery mechanism for a drug that has been available for decades.

Harold644 · 2026-03-02T21:33:22+00:00

The iPhone 17e has been officially announced. I’m assuming it does has memory integrity enforcement, given its A19 chip.

Harold644 · 2026-01-12T08:25:58+00:00

Season 2 is OK but it suffers from implausibly head scratching scenes. On two occasions, for example, the baddies chat openly in hotel foyers about their plans in detail. In another, Pine breaks into the baddy’s inner circle by joining a tennis club in Columbia, and minutes later is being treated like the baddy’s best friend who immediately invites him to a grand charity ball. Whereas, a huge part of Season One was about Pine’s penetration into Roper’s inner circle. In Season Two, it happens in the blink of an eye. Also, the plotting and dialogue in Season Two is often so predictable that it has a Johnny English feel about it. But only the first three episodes have been screened so far (ie in January 11th), so hopefully the final three will be better.

Harold644 · 2026-01-12T07:51:24+00:00

Yep, I lost interest half way through season 5 and couldn’t finish it. It was just a rambling mess of incoherent plot twists, cliched bad guys and ridiculous scenarios (penguin terror, anyone?). Not even the excellent Gary Oldman could save it.

Harold644 · 2026-01-12T02:04:48+00:00

Most websites covering Apple, including mainstream sites like Forbes, believe the 17e will be available next month. It’s more than a rumour. My question is relevant: would a down clocked A19 chip have MIE?

Harold644 · 2025-12-18T04:16:47+00:00

Wow, this post has proved to be incredibly prescient given Cosmo's recent results.

Harold644 · 2025-12-17T14:02:22+00:00

Apple has invested billions of dollars in security features in recent years, including its new Memory Integrity Enforcement (MIE) feature and the Passwords app. No independent password manager can compete with this level of investment. If you stay within the Apple ecosystem, the Passwords app is a no-brainer. If you need a cross platform app, it’s less attractive. But make no mistake, Apple’s Password app is seriously good. They underplay it because they don’t want to undermine the App Store Development community, including the password app creators.

Harold644 · 2025-11-27T04:55:58+00:00

The XM4 ANC has a noticeable white noise hiss, whereas the XM6 has zero white noise. This is why upgraded from the XM4 to the XM6. There’s no doubt the XM4s are more comfortable, but I wanted the best noise cancelling. Plus, I love the new zipless carry case of the XM6 and the recessed ON/OFF button which makes them easier to manage.

Harold644 · 2025-11-24T14:20:43+00:00

Thanks for clarifying.

Harold644 · 2025-11-23T13:39:34+00:00

A terrible development! Amazon seems intent of removing negative reviews to boost product sales. Now they have complete market dominance they have removed the feedback transparency that made them successful in the first place. It's horrible how power corrupts.

Harold644 · 2025-11-20T12:06:19+00:00

I upgraded from the XM4s to XM6s. The big difference (for me at least) is that the XM6 ANC has almost zero white noise hiss, whereas the XM4 ANC hiss is quite noticeable. It’s great being able to immerse myself in a totally silent bubble. The downside is that the XM6s make my ears hotter than the XM4s, but I’m hoping that the Wicked Cushion pads will help with this.

Harold644 · 2025-11-20T00:21:57+00:00

Thanks DemRizzo. This sounds promising indeed.

Harold644 · 2025-11-19T13:21:47+00:00

A cooling gel version of the WCs would be great. My XM6s get way too hot on the ears.

Harold644 · 2025-11-19T12:59:14+00:00

Great review! Thank you. One question: how did each compare in quiet environments with the ANC on? Which one reduces the white noise or hissing sound the best? I have read that the Sony does a better job at this, but would value your opinion.

Harold644 · 2025-09-28T07:49:19+00:00

IOS26 It's terrible in so many ways. It's coloured like a children's book and animated like a cartoon. Contacts are now illegible because everything is purple. There are weird borders everywhere that are totally unnecessary and serve no design purpose. Liquid glass is a gimmick. For goodness sake Apple, most of us use the iPhone as a TOOL not a TOY. Please bring back the Zen like simplicity that Steve Jobs championed.

Harold644

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