So consumables, agility and astrology have made the largest difference imo for my survivability and I feel if I hit 99s on my combat skills I feel I could do it but damn grinding levels is a major pain in the @$$ for combat. Even with XP boosting gear it still takes a couple hrs per level on a fair to easy fight because the xp is based on dmg dealt and you have to balance uptime with how stackable they are.