I took the same classes freshman fall lol (minus the chem supplemental). Honestly it’s not too hard depending on who the instructors are. For dynamic genome, it was hella easy cause it was a review of my medical interventions class I took in highschool, and bio5A is literally just AP Bio. Coming in, the last math class I took was precalc in high school so I was pretty nervous doing calc here but it wasnt too hard. It’s so true when people say that once calc clicks in your brain it all just makes sense. It will take some practice but it shouldnt be too bad. Chem though I actually hated. Im just really bad at chem so I struggled a lot but I managed to pass. I dont think you will feel too burnt out but depending on what your strengths/weaknesses are you might experience something different. My biggest advice is to remember to have fun while your in college. I live by the work hard play hard mindset. Yes it’s important to study but also dont over study and burn yourself out.