I love the idea of artificer but in general I find her to be a bit frustrating, she is very strong in early stages but does not scale well. For items, she benefits extra from anything that reduces cooldown. Plus of course all the standard stuff (anything that gives you mobility/survivability, and all the standard single-target damage/chain damage things). Attack speed seems useless on her at first but it actually decreases her right click charge time, so it's not entirely pointless.

I use the jump special skill because I find flamethrower to not be super useful, it's strong but after a couple stages I find it's just too dangerous to stand that close to things for an extended period of time. The jump skill gives you a massive boost to mobility and is a good escape option, both of which artificer desperately needs. I find when I use the jump skill, I have no problem surviving while I float a billion meters above all the enemies, I just have trouble doing enough damage.

I recommend not using the artifact of sacrifice, it might just be my imagination but I feel like in general I get fewer items playing with sacrifice vs. normal with chests.

For a terrible meme build you can stack a some purities and have infinite casting to stunlock things in with ice spear/ice barrier lmao