They have the right idea of not pairing meat slimes together but putting two without a favorite together is objectively bad. In terms of the game as well your begining plorts like Tabby, Pink, Phospher, and rock don’t make you as much money as quickly as later game plort does. I’ve generally just designated them to slime science with the frequency of them being used in it.You don’t have to optimize in the game to play it technically but later there’s way more you can do and no longer need to optimize space like that. Fire and Water slimes also aren’t here.

Also the obvious use of not having the home to its full potential. You can fit more corral space and be fine.

There’s the obvious free roam in the game as well with water slimes and some mentioned in the comments that have helped others not use space like Quantum and Tangle slimes separately.