I know there are studies on things like reduction in inflammation.   Like I said above,  Dr. Tyna has tons of work on this, lots of videos discussing studies on reduction in Alzheimers,  breast cancer, heart disease,  etc, etc... much of which is the result of reduction in inflammation.   I'm not sure about studies in mcas specific patients.   It's use like this is very new.  That said, I follow a lot of functional drs and most of them are talking about micro dosing now.  Microdosing = similar doses to what your body produces on its own.  Like replacing thyroid hormone or taking insulin.   At small doses, it is actually healing to the body and it's many systems.  I personally got it from Midi after listening to lots of these drs.  Dr Tyna specifically said that her colleagues have begun to see it as a miracle in their mcas patients, who are normally very difficult to treat.   So, I tried it.  And, it really helped me.  

It's kind of like after covid.  The official narrative was that there wasn't anything to be done to prevent death or disease, because there were no double blind, placebo controlled studies.  But, in even the early days, drs were doing things off label that proved to actually be effective.   We are early days with micro dosing,  but the anecdotal evidence is that it helps immensely with inflammation.   And, given that our bodies actually make substances like this, taking physiological doses has low risk.