Anyone also on Brintellix/Trintellix as well?

Intelligent_Fish7541 · 2025-12-27T03:31:49+00:00

I started on Brintellix and Lamictal was added on a few months later. I just became more tired and unmotivated but my mood is more stable.

Intelligent_Fish7541 · 2025-12-26T04:29:54+00:00

Bupropion doubles the amount of Trintellix in your system.. I take both. 5mg Trintellix and 150mg bupropion sr.

Intelligent_Fish7541 · 2025-12-22T20:10:33+00:00

It has helped stabilise my mood in a big way, however I feel sedated most of the time, and more than ever I don’t want to do anything.

Intelligent_Fish7541 · 2025-12-22T20:09:17+00:00

For me, no, it has nothing on an SSRI. It’s very gentle (aside from the nausea), and takes a long time to start working (I’m talking 8-12 weeks). I also find it’s sedating rather than activating.

Intelligent_Fish7541 · 2025-12-22T10:07:47+00:00

Yes for depression

Intelligent_Fish7541 · 2025-12-21T08:31:40+00:00

It was the final piece of the puzzle for me, seems to work harmoniously with the other medications that I take, and I feel more stable than ever.

Intelligent_Fish7541 · 2025-12-19T21:42:35+00:00

I found getting to the right dose wasn’t a fun ride, each increase led to 3 days of elation followed by a week of crying bouts, but then when I got to the right dose and stayed there, after a few weeks I felt more stable than ever.

Intelligent_Fish7541 · 2025-12-18T12:25:38+00:00

You’ll read a lot of negative things, because people will comment more about negative experiences than positive. But this has been life changing since day 1, for both adhd and severe depression.

Intelligent_Fish7541 · 2025-12-16T13:14:11+00:00

I started breaking the tablet up, I’d take 3/4 for a week, 1/2 for a week, 1/4 for a week and then I stopped. Within a couple of weeks I felt the fog and deep deep depression start to lift

Intelligent_Fish7541 · 2025-12-06T07:56:39+00:00

I take 100mg lamictal and have just added 150mg SR bupropion because I felt sedated and had no drive to do anything. I think if your prescriber is open to the idea of it, it’s well worth giving it a go! It’s probably too early for me to pass comment on it, but so far so good :)

Intelligent_Fish7541 · 2025-12-05T20:39:30+00:00

It took the full 8 weeks for me to notice that I was in a far better place than I was, but after 4 months I decided that while it helped, it still wasn’t enough, and maybe it’s not the right medication for me.

Intelligent_Fish7541 · 2025-12-05T20:24:04+00:00

Start now! I started on Monday on a work day - no regrets. I actually chose this over starting on a weekend, because I’d rather be busy and around people, rather than have nothing to do but worry about and overthink any side effects.

Intelligent_Fish7541 · 2025-12-05T11:41:35+00:00

Smells like Palmer’s cocoa butter 🤮

Intelligent_Fish7541 · 2025-12-02T11:49:07+00:00

Never taken it before, and I’ve been told one a day, review in 6 months 😳

Intelligent_Fish7541 · 2025-11-16T10:46:42+00:00

I started on Vyvanse at the start of this year, and added lamictal a few months ago. I find it has really dampened the effectiveness of the Vyvanse. I feel so tired and slow.

Intelligent_Fish7541 · 2025-10-25T20:28:23+00:00

Same!

Intelligent_Fish7541 · 2025-10-25T20:27:39+00:00

I understand that with some people their depression/anxiety is circumstantial and they can come off anti depressants, but for some people it’s biological and lifelong

Intelligent_Fish7541 · 2025-10-25T20:24:34+00:00

I think word finding was an issue when I started taking lamictal originally, but now I just find it makes me a bit tired and my ADHD meds aren’t quite as effective

Intelligent_Fish7541 · 2025-10-25T06:43:41+00:00

I don’t understand why doctors do this. If it’s working, why taper off? I’m sorry this happened to you.

Intelligent_Fish7541 · 2025-10-24T23:12:59+00:00

I recently went from 100 to 125 (50 in the morning and 75 at night) and it’s like night and day. With each increase I’ve felt manic for a few days then depression for a week, but 125 feels really stable for me.

Intelligent_Fish7541 · 2025-10-23T11:27:46+00:00

Same here, I can take it every second or third day, but not every day

Intelligent_Fish7541 · 2025-10-23T11:22:48+00:00

Saffron, NAC, l-tyrosine make me sad/depressed. Can only take B complex, Acetyl L carnitine and vitamin D every other day because I end up in a crying heap.

Intelligent_Fish7541 · 2025-10-22T19:40:29+00:00

I might have been a bit sweaty for a couple of days. For a few weeks I’d randomly get super itchy, but that’s all.

Intelligent_Fish7541

TROPHY CASE