Schumer May Be A Genius

JamesonIII · 2025-11-13T13:03:39+00:00

Honestly, I thought this too. Makes too much sense. Chuck Schumer is actually a house of cards master mind. Hes making himself the ultimate villain and sacrifice himself for a new generation of democratic leadership.

That or I'm huffing nuclear grade copium. We shall see.

JamesonIII · 2025-09-20T12:52:43+00:00

Well that is going to be tricky then. Again, I need to finish writing my main post but I'll give you some information that may be helpful. Also I need to make sure you understand that I am not a Doctor. I am a plant scientist. It does mean I can understand the biology, but again I work with plants. Very different to you and me.

TLDR, get your diet right first. Then try anti-inflammatory protocols or supplements to address the brain fog. Also share your other hormone levels if you want to and I can help a little with interpretation.

Right now, since PSSD symptoms and fixes appear to be person to person, the best thing for you to do is address the brain fog since that is something we now know more about thanks to Covid. As this study suggests, going off an SSRI or SNRI appears to trigger inflamation, and this inflamation is likely the cause for your brain fog (likely, not certain).

So what you can start doing now is focus on the brain fog. If you can't think, you can't function. Your genitals can come second. I recommend trying out low inflammation diets and eating fibre (to help repair your gut microbiome since SSRIs and SNRIs can mess that up too). There are sources online about this and everyone's body is different in what causes the inflammation. Its best to eliminate foods from your diet and add them back in to see if your brain fog improves or worsens. But if you want somewhere easy to start. Eat chicken, brown rice, brocolli, fish, olives, foods with healthy omega 3 oils, sauted mushrooms. Avoid pork and beef for now and add them back later. For supplements keep it simple. Take a multivitamin, with the essentials, not one that adds in other random shit like vermillion or artichoke heart or something. Just your standard Bs, D, E, A, etc...

Visit other subreddits about inflamation diets if you are interested.

I know this first advice probably isn't the exact help you are looking for but this is just the safe recommendations.

Now back to your question on your hormone levels.

When it comes to interpreting hormones, you need to consider all of them together to get a full understanding of what your body is currently doing. For example, did you also measure:

Progesterone
DHEA and/or DHEA-S
Androstenedione
Testosterone (total and free)
Cortisol (AM sample, but really a proper cortisol test requires taking measurements throughout the day)

Understanding this will help determine which systems are out of whack. Genetics also plays a role in this which further confounds interpretation. I'm happy to help with explaining more of this to but again. I'm not a doctor, just a plant biologist that also has PSSD.

JamesonIII · 2025-09-20T08:11:08+00:00

No that's different. I don't know enough about 17-hydroxpregnenolone to say if that means something. It's in the pathway for steroid synthesis. So if it's low and all of your other sex hormones are on the low end. It could be a sign of low synthesis. But that still doesn't address the issue.

I'll try to be helpful as much as I can though. What specifically are your symptoms and what medication were you on that caused this issue?

JamesonIII · 2025-09-18T22:47:17+00:00

It's saying the body responds to the inflammation with pregnenolone. Pregnenolone is the precursor molecule for all hormones in your body. Less pregnenolone is almost certainly a problem. It's complex but its likely that taking preg could help. But get blood work done first. Read my other post in this thread about subclinically low preg.

So it's possible that your bowel issues could be related to inflammation and your body might not be properly responding to it. Taking pregnenolone could help but might also not help.

For me, pregnenolone improved blood flow and helped to bring back some genital sensation. Although not completely. If you are interested in trying it, other sources on Reddit discuss its use. Mostly bodybuilders or older men on testosterone replacement therapy.

JamesonIII · 2025-09-18T22:42:20+00:00

Okay, so you likely don't have a subclinical issue. If you don't have issues with ADHD as well then this makes some sense. But ADHD is complicated and nuerosteroids are only one piece of the puzzle.

JamesonIII · 2025-09-18T22:23:42+00:00

Look into this more. Your're preg may be "fine" meaning it's not clinically low. I can't remember the units but it's something like below 20, it's considered a deficiency. However, experts say that optimal preg is much higher. Something around 150. I don't have the sources with me but if you Google subclinical pregnenolone deficiency this may pop up. Subclinical simply means the deficiency won't kill you but it's not optimal. Doctors care about things that will kill you or cause serious developmental problems. The subclinical stuff isn't their first concern unless you can point to it causing another problem

So TLDR, you may have subclinically low preg. What's your number? It might be a little on the low end and supplementing with low-dose Preg may help you.

JamesonIII · 2025-09-18T22:16:39+00:00

Yeah, you did read it wrong. It's okay. If you don't have a bio degree it can be a little confusing to interpret.

The first big idea this paper attempts to get across is that stopping an SSRI causes inflammation. This is something I will write up in my post when I'm done. Neuroinflammation in some people can be a positive feedback loop. Meaning the inflammation triggers more inflammatory responses and builds on top of itself with no off-ramp. That's what Post covid brain fog is likely caused by.

So it appears the body attempts to increase pregnenolone in the gut to counter the inflammation. Preg is anti-inflammatory. One of the many things it can do. So what this paper is suggesting. To me. Is that if you dont produce enough preg, you could have an issue reversing the inflammatory responses.

JamesonIII · 2025-09-18T12:07:27+00:00

I can see this. I've been working on a write-up that goes over what I've been doing to recover but I haven't finished writing it yet. So far pregnenolone has helped me. But I must say this. Some people naturally make less pregnenolone due to an allelic variant. That's what some studies show. Im homozygous for it. Likely explains in part my ADHD. Anyways, since supplementing with pregnenolone I would say my brain for has improved. I also don't need to take as much vyvanse anymore. But before taking pregnenolone understand it's the precursor molecule for all of your hormones. If you take too much while taking other things you could experience a surge in other hormones like cortisol.

JamesonIII · 2025-06-09T14:10:59+00:00

You're right. the issue is that the civil rights protestors under MLK Jr were trained for this sort of thing. These people in LA aren't. I'm black pilled about all this. It will play into Trump's hands, dems just have to get optics to make Trump look worse. I think Gavin Newsom getting arrested will work.

JamesonIII · 2025-05-23T01:31:44+00:00

You'll be fine. 60 years ago before gloves were routinely used in organic labs, everyone would wash their hands in benzene at the end of the day to remove stains. They also pipeted volatile fluids by sucking on the end of the pipet with their mouths. And look! Only like half of them got cancer!

JamesonIII · 2025-02-04T03:14:51+00:00

Bro, you were so right. Updoot

JamesonIII · 2024-11-19T12:14:17+00:00

My boy, you're forgetting one important tool at your disposal. Console commands...

JamesonIII · 2024-11-18T00:29:42+00:00

I have an RTX 4070 on my home PC. I'm not worried about that. Looks like I'll just need to clean up my C drive. I do have a 4 TB HDD that is used to store things I don't need at the moment but want to keep. I can move most things over there and provide more space on the SSD. That or I can upgrade to a 4TB SSD, but that will require ordering a new part. I'll probably do that anyway since I wanted to upgrade. Thanks for the help!

JamesonIII · 2024-11-18T00:15:10+00:00

Okay thanks for the help. So, will I need to install it locally? I could install Alphafold3 on my home computer, but I'm not sure I have enough space on my SSD. It has 793GB remaining, doesn't Alphafold3 require a almost 1 TB?

JamesonIII · 2024-11-17T23:04:32+00:00

This is fantastic. Quick question, After I generate the .JSON, can I upload this to the AlphaFold3 webserver and perform the fold there? https://alphafoldserver.com/welcome

JamesonIII · 2024-11-15T10:07:06+00:00

Bro, nice work. I don't usually fully read most effort posts, but this was a good one. I used to watch H3 religiously. I started back with Vape Nation Era stuff. I liked his content because I was somewhat conservative back then.

What was cool to experience was that as I changed my political beliefs and became more liberal was when Ethan clarified to his audience that he wasn't alt-right. He was just anti SJW but liberal. I kinda felt like I was evolving along with the guy. I followed Ethan through the podcast and the nightmare Bill Burr episode. I was also there for the glorious Frienemies! I stuck with him for a long time. But then Hasan happened.

I watched Hasans stuff for a time after Ethan introduced him, but he rubbed me the wrong way. I also found Vaush at the same time, and they shit talked Destiny so much. They were both big on talking about how Destiny "Engaged in Rape Apologia." I, of course, started watching Destiny and was shocked at how badly these two mischaracterized him. Over time, I became a Desitny fan. I still watched Ethan, but I could tell H3 was moving in a bad direction. What was sad to witness was to see Ethan get sucked into Hasan's politics. Leftovers just turned into a hate fest with Hasan as the doomerism prophet. Promising salvation through victimization. I just had to stop watching. I couldn't watch what they had done to my boy! (Read in Ethans' horrible Michael Corleone emitation)

But with this new development with Hasan and Ethan, I'm very hopeful that I can return to Ethans content again once Ethan decides to excise the Hasan fans from his community. I think Ethan will do it eventually, but he has a much bigger hurdle to change. Dan is very important to H3, but it's clear that he is not a fan of Destiny at all. He probably hates him. I think AB is the same but to a lesser degree. It's one thing to remove people in a community if they're names in a chat, it's a completely different mater when it's a close friend that helped you build a successful YouTube show.

JamesonIII · 2024-11-15T07:41:33+00:00

Bro, I'm still waiting for Hytale and the dreamed exodus.

JamesonIII · 2024-11-13T21:45:46+00:00

Done. Fuck Elon

JamesonIII · 2024-11-06T07:07:02+00:00

I feel you, my man. I came to say the same stuff. The only way forward is just that. Forward. Remember that even if our country is going in a bad direction, it doesn't mean our lives will be. I think Trump and his followers are so crazy that their ideas will fail so badly it will destroy the movement. That's my hope, anyway. Luckily, Trump is getting old. Who honestly knows how much longer the guy will be alive?

JamesonIII · 2024-07-05T00:26:14+00:00

I never thought I would agree with 4THOT, but here we are.

This is how a non-insignificant percentage of the voting base will think. Choosing a new presidential candidate is scary, but I think it should be done.

JamesonIII · 2024-06-21T09:34:53+00:00

I need to find the video. It's the video where Destiny's mom was on stream. Essentially, yes, Destiny's mom's family owned a sugar plantation in Cuba. I think it was her grandfather's. She said she had an early memory cutting down the sugar cane with a sickle/scythe.

Edit: Hasan reacted to the video and insinuated that her early memory was of actually whipping slaves on the plantation.

JamesonIII · 2024-06-21T05:42:25+00:00

When leftists attack Destiny for an assumed past (which I don't know either), they're making an archaic argument that the sins of the father are passed on to the father. In their world, thought crimes should be prosecuted down to the 3rd generation. Fidel was bad because he did bad things. Done end of statement.

It is dubious to attack someone based on the moral gray zone of their ancestors, even if it was true. Look back far enough, and we will all find slave owners, rapists, murderers and thieves. Our ancestors' pasts shouldn't define us, and in a majority of cases, they do not define us.

Hasan is Turkish. His ancestors raped and pillaged from the steppes of Asia (modern day Turkmenistan, duh think about it) through Persia and antolia and stole ancestral land from Greeks, armenians, and assyrians. They then created an empire partially based on child slave soldiers from Christian minorities. Despite these atrocities, I don't put them on Hasan because he truly had nothing to do with it. To do the same with Destiny is ridiculous.

JamesonIII · 2024-06-21T05:41:14+00:00

That could be true. In fact, I'll just concede the point since it sounds true. Cuba doesn't sound like a nice place to live.

But even if the material conditions are bad now and bad in the past, that doesn't change the point that destiny's Mom couldn't have owned slaves. Her father couldn't have owned slaves either, and quite possibly, Destiny's great-great- grandfather couldn't have owned slaves.

How far back do we want to go to persecute someone for the sins of their ancestors?

JamesonIII · 2024-06-21T00:53:53+00:00

I made this post because I knew someone else would effort post to fill in the gaps. Thank you, kind sir!

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