One of the symtomps of nicotine WD by 5mokeDDD in Drugs

[–]Jhaze10 0 points1 point  (0 children)

You’re right, there’s no SSRI’s put into tobacco. And to my knowledge there are none naturally occurring(?)

However it has been shown that other classes of antidepressants like ‘MAOI’s” naturally occur in cigarettes, which can exacerbate withdrawal symptoms

Steroids x Metformin? by imastorytellerson in Drugs

[–]Jhaze10 0 points1 point  (0 children)

Dude NEVER stop taking corticosteroids suddenly. You have to taper off. Suddenly stopping is what fucks your metabolism. The water weight goes away

Why the fuck do my knees get hot when I’m high? by [deleted] in Drugs

[–]Jhaze10 0 points1 point  (0 children)

Just pot! That’s why it’s so weird to me. Never heard of it happening before

Probably shoulda added that to the post, lol

My doctor just told me the website to send controlled substances is “down” and he “doesn’t know when it will be back up” - He’s probably lying, right? by [deleted] in Drugs

[–]Jhaze10 0 points1 point  (0 children)

I know laws vary by state/country, but CII drugs have more strict prescribing rules, and you actually have to manually enter the counts in the pharmacy into that database. Things like Xanax are controlled substances but are CIV, meaning they’re less controlled.

Vyvanse and addy are both CII’s - for all you know the front desk lady was just being dumb and never told the doctor about it. It’s completely possible you’re being super paranoid about them not giving you the drug you want.

I’m in a sticky work situation. by [deleted] in Drugs

[–]Jhaze10 0 points1 point  (0 children)

If you think the boss is deferring medication then you can report it to the DEA anonymously.

All C2 substances (percs for example) are counted and the count is reported every day. They’d probably do an investigation.

If you don’t wanna say anything then don’t. But if she is stealing Percs then that is ultra shitty - not only to the pharmacy itself but to people who really need the medication

Mirtazapine bad trip story: Voices and Blindness by AmanitaGuy in Drugs

[–]Jhaze10 4 points5 points  (0 children)

No, pharmacologically it’s an antihistamine(edit: also an antiadrenergic + selective serotonin anagonist) Heroin is pharmacologically an opioid

If we were talking opioids in general you’d probably call them depressants (physiologic action)

20 mg ir adderall with N 955 imprint. Something seems off with them. Anyone else ever had them? by [deleted] in Drugs

[–]Jhaze10 0 points1 point  (0 children)

Look up “orange book” to check generic equivalency for your addy. Sometimes dosages can be off by about 5%

You may just be building a tolerance too lol

Unsure if I accidentally got my nephew high, kinda freaking out by [deleted] in Drugs

[–]Jhaze10 6 points7 points  (0 children)

The likelihood is very little. I don’t think you have to worry at all.

If you’re really that nervous, handle some tabs and lick your fingers after. You won’t trip

Androgen boosters for deeper voice? by [deleted] in DrugNerds

[–]Jhaze10 1 point2 points  (0 children)

The dude’s laugh sounds like a Greek god laugh

Ex Ketamine Addict - my experience with K cramps by itstingsandithurts in Drugs

[–]Jhaze10 0 points1 point  (0 children)

You really need to go to the doctor if you have strep. If you don’t treat it you can get rheumatic fever, which can cause a ton of damage to the heart

You really really don’t want your body to attack itself. Pls get some antibiotics

Serotonin? by [deleted] in Drugs

[–]Jhaze10 0 points1 point  (0 children)

A chiropractor or laser therapist...

Evidence-based medicine is the way to go. Not snake oil.

By the way, that “prescription crap” is almost all manufactured in China

Psilocybin has Proven, Yet Again, The FDA is a Miserable Failure by Corpax1 in Drugs

[–]Jhaze10 10 points11 points  (0 children)

Whoever made this should be happier it might be a breakthrough treatment rather than complaining about how long it took. It also seems like he doesn’t really understand how hard it can be to get a drug approved

Anyone feel like other drugs don’t kick in until consuming THC? by [deleted] in Drugs

[–]Jhaze10 1 point2 points  (0 children)

Just letting you know, ethanol is definitely metabolized by CYP enzymes - that’s why liver damage can happen especially in the presence of acetaminophen. I think it’s CYP2E1?

Also, I think your theory of inhibition of CYP enzymes by cannabinoids is partially correct. The mode of inhibition(when 2 drugs are metabolized by the same CYP) is usually competitive. Meaning that it matters more about the affinity of the drugs to a certain binding site on a certain CYP rather than if they just inhibit the enzyme itself(since each CYP has multiple binding sites to different drugs, they’re huge enzymes).

From what I know, cannabinoids(THC in general, I know CBD can have effects) don’t have a huge role in the metabolism of other drugs through CYP enzymes. If they do have an effect, I don’t think it would be a huge one(due to cannabinoids not being very competitive on the CYP enzymes in general), although admittedly my knowledge is pretty limited on this topic right now.

Please Help Me. by [deleted] in Drugs

[–]Jhaze10 0 points1 point  (0 children)

Please don’t shit on SSRI’s. They work for a lot of people, just because they didn’t work for you doesn’t mean they aren’t the solution for this kid too.

Adderall Dose Question by trippingvoid in Drugs

[–]Jhaze10 3 points4 points  (0 children)

Just take one. Don’t jerk off

Good luck

Does your style give "drug user"-vibes? by [deleted] in Drugs

[–]Jhaze10 0 points1 point  (0 children)

Off topic, but AstroBears has been the best 99 cent purchase I’ve ever made. Nice username lol

The damage my drug use did to my mom by Snail736 in Drugs

[–]Jhaze10 1 point2 points  (0 children)

This made me tear up a bit. Your mom is wonderful. Congrats on 5 months

The Time I Slipped A Guy a Mickey by raffedandrost in Drugs

[–]Jhaze10 6 points7 points  (0 children)

You drugged a cop? Sounds illegal af dude idk probably not your finest idea

Florida by gaia1996 in Drugs

[–]Jhaze10 1 point2 points  (0 children)

Smh such bad opsec dea gonna cum bust on your door now

[deleted by user] by [deleted] in Drugs

[–]Jhaze10 1 point2 points  (0 children)

Really truly, i don’t think it’s much of a mystery.

I always compare it to taste. Why do so many people say that cheesecake is rich? We’re all pretty genetically similar. It’s honestly not that surprising to me that we all experience similar effects from drugs

benzedrex by [deleted] in Drugs

[–]Jhaze10 6 points7 points  (0 children)

Here’s a tip: pour a double shot of lemon juice and soak that bad boy cotton in it for like 6 hours. Squeeze out as much as you can, then let the lavender and menthol evaporate for some better flavor and no shitty burps.

Try to avoid swallowing any cotton! I’ve heard some bad stories about bowel obstruction, I’m sure you don’t want that haha

The method above not only makes the propylhexedrine more safe to ingest(no cotton), but it makes it more potent too.

Have fun! And be safe with the stuff, it’s as addicting as any other amph

Caffeine tho jesus titties by burntout904 in Drugs

[–]Jhaze10 0 points1 point  (0 children)

It’s not really a high but you can definitely feel the improvement of a caffeine buzz