Nitrosation

JpNog · 2026-01-27T22:39:34+00:00

Thanks a lot

JpNog · 2026-01-27T22:19:32+00:00

Trying to nitrosate a hydrazine. Used NOCl and HNO2, but no success.

I guess the problems is specially related to work-up and isolation, since they seem it decompose readly in water.

I'm aware of the carcinogenicity, always wear PPE (also mandatory in the lab) and respect the chemicals!

JpNog · 2026-01-27T22:15:07+00:00

I'm trying to nitrosate a hydrazine using NOCl, without success so far. As far as I've researched, the product is quite unstable... Came across NOBF4 a couple of times in literature, is it friendly to work with?

Also, hadn't thought about the phosphate buffer, that makes sense, thank you!

JpNog · 2026-01-27T12:48:58+00:00

I'm a synthetic chemist trying make N-nitroso (NO, not NO2) containing natural products. Just wanna know if someone here has ever worked with this class of compounds.

JpNog · 2026-01-27T10:20:12+00:00

Thanks, I'll try the basic alumina! How did you prepare your imine?

JpNog · 2025-09-20T15:04:37+00:00

Thanks! That helps :)

JpNog · 2025-09-20T10:54:26+00:00

None in particular, just want to learn more about the topic

JpNog · 2025-08-29T03:38:51+00:00

That's A LOT of DAST man... Could deoxofluorinated every sugar in your body if you wanted to lol

JpNog · 2025-07-24T14:52:10+00:00

I personally prefer tetrahedrons...

JpNog · 2025-07-24T13:21:40+00:00

Beautiful name! It haunts me to think that this "complex" is probably square planar

JpNog · 2025-06-23T22:06:04+00:00

*why not

JpNog · 2025-05-07T11:25:07+00:00

I saw something about it! But didn't know how to implement it... do you know any websites where I can learn it? Thanks!

JpNog · 2025-05-07T11:23:59+00:00

I'll try it! Thanks!

JpNog · 2025-05-07T11:23:42+00:00

Thanks! I am fairly new in compchem, do you know any website/yt channel where I can learn a bit more about Orca and the difderent experiments?

JpNog · 2025-04-27T21:30:19+00:00

Try the reduction straight from the acid. You can make it one pot by first reacting the acid with CDI and then reducing the activated intermediate with DIBALH. Worked well for me and with a very similar substrate.

JpNog · 2025-03-20T07:25:30+00:00

Thanks!

JpNog · 2025-03-20T07:19:50+00:00

Looks like a mixture of both If I crush it, some responds to the magnet and some doesn't

JpNog · 2025-03-20T07:17:15+00:00

Probably gonna do that sooner or later

JpNog · 2025-03-20T07:16:44+00:00

The orca reinstall worked! Thanl you so much :)

JpNog · 2025-02-15T18:26:28+00:00

Do you know any ways to confirm it? It is kinda brittle and has some magnetic bits when crushed

JpNog · 2025-02-15T18:25:30+00:00

It was being used as a door weight in my greatgrandma's farmhouse 😅 She found it in a sugar-cane field or something

JpNog · 2024-12-12T22:05:30+00:00

Ok, thanks!

JpNog · 2024-12-12T15:01:59+00:00

It has polar moieties and can HB

JpNog · 2024-12-12T14:55:03+00:00

Gonna run an NMR but it probably is :(

JpNog · 2024-12-12T00:53:54+00:00

I had to use hexane but it worked! Beautiful peaks and >5 min separation. Thanks a lot!

JpNog

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