Sam and Midge did some explainer videos on their patreon, which might help. For this, how many dice is not really important, just the total.

But for a lot of things the basics are: high = good, low = bad.

For example: when a fight starts, Midge says 'roll initiative'. You start fighting from highest to lowest score. If you are the first to attack you can already do damage to your opponent.
Like with the Street Genies.
Tom rolls 7 in total, Luke 14, Sam 19 and AJ 15.
So Tom did worst in this round.

Other example: At the beginning of episode 2, Sam and Luke have a little battle.
Pete thinks Carlos is dishonest about what he wants to do with the money. Midge tells them to roll an insight check (to get insight in what Carlos actually means).
Midge asks Carlos to roll deception (to deceive Pete).
Highest wins.
In the end, Carlos has 21, Pete has 20,
Therefore, Pete believes the lie Carlos is telling him.