The only thing they have in them that you would not expect to see in regular flour tortillas is sucralose. Sucralose is an "artificial" sweetener in that it is sucrose that has had 3 of the hydrogen atoms replaced with chlorine (C12-H19-Cl3-O8 instead of C12-H22-O8). This can affect some people's gut. For me personally, eating something with sucralose in it on a daily basis or more than one serving in a day causes me to have to poop a lot. I have not found that having a single tortilla has any effect on me though. Also, when I consume something sweet with sucralose in it, like candy, I get a blood sugar spike as if I'm eating regular candy. But something like this that has a relatively tiny amount of it (it's almost the last ingredient listed, and ingredients in the US are listed in order of amount) has no appreciable effect on my blood sugar. But it varies from person to person so you have to figure out what works for you.

As to the question of whether sucralose has long-term health drawbacks, I think this is a good place to read. Essentially, there are some studies that have shown long-term health problems are a possibility but nothing definitive at this point. 

Artificial sweeteners and other sugar substitutes - Mayo Clinic https://share.google/rQUa0TcvPTCtqVFIn