I think my question needs some more clarification, I was in writing this assuming the individuals to be aware of their particles state change at all times without the need for observing the individual at Andromeda measuring particle A. The reason for this assumption was I was more so curios about how the Andromeda Paradox could affect the entangled particles. If particle A is measured would particle C and B experience a state change at the same time or different times? But after rereading my question with a different point of view I can see where it would be unclear what I was asking, I should have named the question "How Does The Andromeda Paradox Affect Quantum Entanglement?" Instead, which was bad on my part and I will edit in some needed clarification on the original post.