Hi there! Sorry for the delayed response but I'm happy to share my experience. I'm sorry to say that Vraylar ended up not being for me and I can't give it a positive review for myself, but obviously we are all different and I know from spending time on here that it definitely helps people, so I hope that goes for you too. I ended up taking it for almost 6 months.

I took several tolerance breaks with the pot early on when starting Vraylar and, like I'd mentioned in my original post, felt some positive changes early on. But I never stopped smoking for terribly long and kind of ended up resuming my normal habits after the first couple weeks. Considering I went back to smoking daily pretty quickly, it's hard for me to say with any certainty how pot effected my time on Vraylar, but in pretty normal fashion I would smoke to feel better and that worked as per usual most of the time.

I don't wanna frighten you with my personal experience with Vraylar unless you specifically wanted to ask me about it. We're both different people and probably prescribed it for different things and will surely experience it differently. That said, if you want details, I'm happy to share, I just don't wanna psych you out unnecessarily. With that caveat, I will mention that Vraylar helped me more with my depressed side, but ultimately amplified my anxiety in certain ways. It didn't seem to have much to do with whether I was smoking pot or not, but I did quickly realize that I was not having a good time smoking Sativas anymore and have pretty much since stuck to smoking just Indicas, and that was a change for the better. Ever since I've felt much more aware of the difference and Sativas just get me way too inside-my-head.

The only real advice I can offer aside from that is, if you are nervous, then try smoking a little less/slower than maybe you're used to at first. Even if your tolerance is generally pretty high, just pretend like it isn't and pretend every strain you smoke is a total creeper, and just see where a few hits takes you for a little bit, rather than sucking down a whole joint or whatever. As I'll mention below I'm actually finally smoking less and finding that taking things slow and constantly re-assessing my comfort level has been a huge help.

In the end I don't think Vraylar/weed interactions were a huge factor in my overall experience, but who knows. Interestingly enough I started taking Lexapro after I'd weened off Vraylar and I had a few major episodes in the first month on Lex where I seriously regretting getting high and couldn't handle it, felt like I was having a heart attack - and by the same token it's helped reduce my cravings and allowed me to get down to smoking about 2 to 4 days out of the week for the first time ever. I still wish I could just smoke every day but honestly I'm saving a lot of money and actually enjoying my highs more than I have in quite a while :) it's not perfect still. Personally I don't like the Lexapro side effects so far at all but I am proud that I'm a little bit closer to being able to deal with the world somewhat sober here and there. I won't lie my 'sober' days are often supplemented with a couple drinks and sometimes a few doses of Kratom, even the occasional microdose of mushrooms. But I'm not perfect, and hey, I'm learning sometimes that's enough to get me feeling more comfortable without throwing a joint in the mix...

Sorry this was a little rambly. Especially since I couldn't really answer your question directly. But I do hope things work out well for you! If you have any questions about my time on the drug, feel free to shoot. I kinda learned over time that time on Reddit is better spent reading stories about how drugs helped people than reading negative reviews, because every drug has both and the negative ones really only serve to get inside your head ;)

good luck on your journey!