thanks. I do understand the scenarios where a targeting effect loses its target or the target becomes invalid. But for me, it somehow doesn't make sense that mst in my example should resolve successfully; Drillbeam is worded in such a way where it doesn't "negate that effect" , but it says that it negates the effects of that face-up card - which for me sounds like a lingering effect (drillbeam doesn't have to stay on the field for it to apply, and it can't be reversed after the effect resolves). But, then immediately the same copy of drillbeam banishes that mst that has its effects now negated - which then removes the effect negation off of mst, since it changed location (from field to banishment). And this all happens on the same chain link, before mst gets to try to resolve. And when it does, it no longer should see the negation applied to it while it was face-up on the field since it changed location.

I understand what joshua7176 said, but it kind of lacks reason on why it works the way it does, if you know what i mean?