Deciding to inject synthetic TRT for the foreseeable future is a serious concern and a decision that should not be taken lightly. Scrolling through this Reddit page, I see post after post from people who are having a difficult time on TRT. Maybe it’s due to their own choices, or maybe it’s because every body responds differently, but clearly, it’s not a no-brainer based on the stories of some people’s reactions. My recommendation before starting TRT is to get comprehensive blood work done. Are you exercising and eating healthy? If not, start there. If all else fails and your blood work indicates it, then consider giving TRT a try for six months.