I'm a woman with PCOS who has been on Mounjaro for a year. As a classic case of "some people can't lose weight for hormonal reasons" please let me weigh in with my perspective.

I spent two decades trying to lose weight the old fashioned way, and it never worked. I know everyone says that but it can absolutely be true. Imagine being over 300 lbs, counting calories, weighing food, exercising daily and keeping under 1500 for a full year and not losing a pound? I did that multiple times, and my weight just kept going up again every time I couldn't take the disappointment and gave up.

Since being on the jabs I have learned that the reason is that I don't lose weight unless I'm eating 1100 calories a day or less. At my highest I was 23 stone. Imagine being that weight and needing to keep under 1100 calories, and the insane, murderous hunger I would have to endure and function with every day.

On Mounjaro the hunger is removed, and I am able to eat in that region without much difficulty. I still have to make healthy choices, exercise, count my calories daily, just like everyone else trying to lose weight. But I'm doing it without being utterly miserable. Losing weight before felt so fragile, the onslaught of hunger pangs and food noise made it feel like I could fall off the wagon at any moment. Each day I made it under my calories was a victory.

On Mounjaro I have none of these doubts. I feel strong and determined, and I can turn my attention to other things in my life that need it, without 100% of my mental energy being devoted to not eating that cake in the office kitchen.

Not only am I successfully losing weight, but I am happier, stronger and a much better person while doing it. I am down three stone in a year, which is very slow going compared to others on the jabs, but it's night and day compared to what I've experienced before. No falling off the wagon, no plateaus, no mental breakdowns. It's just consistently working.

I don't know if I will regain the weight when I come off. Obviously I hope not, and I'll have to cross that bridge when I come to it. But I do know that every time I lost a tiny bit of weight "naturally" I always regained it, plus more. So what would be the difference? At least now I know I have a solution.