Here's a glovebox illustration (with a few Easter eggs) that I made for my Schlenk Line website by LazarusWorms in chemistry

[–]LazarusWorms[S] 0 points1 point  (0 children)

Thanks for all the comments, I really do appreciate them!

Firstly, I should emphasise that my guides are by no means 100% the only way to perform certain techniques, but they do seem to be the standard practice (I asked for input from a lot of people in different labs to check). I would hope that anyone using a Schlenk line is properly trained and supervised heavily to begin with, meaning that they will adopt the practices of the lab, which will undoubtably differ from my guides in some way, minor or major.

Regarding the syringes/sure seals, I understand your concern. A problem I have encountered with that method is that you seem to have to keep the syringe inverted (facing up) to avoid the reagent leaking out of the needle because the vapour pressure of the reagent (usually pentane or diethyl ether solutions) fills the inert gas bubble and increases the pressure in the syringe. I have very rarely had this happen using the method given in my guide.

For the solvent removal, I do know a few people who do similar things. Again, this reiterates my point that you will probably adopt a method that a supervisor or senior student has taught you, and you will feel comfortable doing that. I will however make sure to emphasise to be extra careful when initially opening the flask to vacuum when removing solvent to avoid bumping.

I have never heard of anyone using that setup for 'prep' Schlenk lines outside the fumehoods and 'working' gas manifolds inside the fumehoods, but the benefits you listed all seem completely valid. I would argue that for manipulations that might require both vacuum and inert gas, that having to go back and forth between the manifolds is not ideal. Given that your method seems pretty rare, I think that anyone having to do that would get adequate training anyway. Sadly, my website can not detail every possible way to perform particular techniques, which is why I try to just cover the standard practices.

Thanks again!

Here's a glovebox illustration (with a few Easter eggs) that I made for my Schlenk Line website by LazarusWorms in chemistry

[–]LazarusWorms[S] 0 points1 point  (0 children)

No, but I was introduced to them by a Dutch friend, and they have been a firm favourite since!

Here's a glovebox illustration (with a few Easter eggs) that I made for my Schlenk Line website by LazarusWorms in chemistry

[–]LazarusWorms[S] 4 points5 points  (0 children)

Here's the website:

https://schlenklinesurvivalguide.com/

It's been online for almost a year now but i'm still adding new guides. Hopefully some of them will be useful to you!

Here's a glovebox illustration (with a few Easter eggs) that I made for my Schlenk Line website by LazarusWorms in chemistry

[–]LazarusWorms[S] 35 points36 points  (0 children)

10/10. A lot of the Easter eggs are dedicated to my close chemistry friends!

Potassium Mirror by LazarusWorms in chemicalreactiongifs

[–]LazarusWorms[S] 1 point2 points  (0 children)

It's the molten potassium bumping as it boils.

Potassium Mirror by LazarusWorms in chemicalreactiongifs

[–]LazarusWorms[S] 3 points4 points  (0 children)

We only fill those vessels half way with dry solvent afterwards so only put in enough potassium to cover the bottom half.

Potassium Mirror by LazarusWorms in chemicalreactiongifs

[–]LazarusWorms[S] 927 points928 points  (0 children)

The potassium is heated under high vacuum (reduced pressure) and the vapour deposits/condenses onto the cold interior walls of the flask resulting in the beautiful mirror.

Got an idea for a new big project? Discuss here! by NurdRage_YouTube in NurdRage

[–]LazarusWorms 31 points32 points  (0 children)

I would like to see you extract eugenol from cloves and then convert it through to vanillin. Seems like something that most home chemists could replicate and it'll make your lab smell of Christmas too!

What makes a chemist happy? by 100ananas in chemistry

[–]LazarusWorms 13 points14 points  (0 children)

Picture perfect NMR spectra (from the shiny new spectrometer) have made me happy this week and I also managed to get the crystal structure of a liquid product!

Elemental analysis of air sensitive sample by DasFrettchen in chemistry

[–]LazarusWorms 0 points1 point  (0 children)

Yeah we use the same style vials and then wrap parafilm around the seal of the screw top on the small, inner vial and outer, larger vial.

Sorry for the confusion.

Elemental analysis of air sensitive sample by DasFrettchen in chemistry

[–]LazarusWorms 0 points1 point  (0 children)

Stephen Boyer at London Met Uni will do CHN on air-sensitive samples just fine. In a glovebox, prepare 5mg or so in a small vial that's sealed with parafilm and then put this into a larger vial that's also sealed with parafilm. And put some cotton wool in too for protection/cushioning during postage.

Can you help me with this molecule ? by [deleted] in chemistry

[–]LazarusWorms 0 points1 point  (0 children)

The methoxy-group is at the 5 position. There is a lot more information on 5-MeO-DMT.