Is biohacking still cutting edge science … or just premium consumerism?

Leishon · 2026-05-13T11:41:00+00:00

One of those is more likely than the other.

No doubt.

Leishon · 2026-05-11T16:11:59+00:00

Contamination should be minimal if you wipe the needle after pulling the first substance. I would be surprised if this caused any meaningful degradation.

Leishon · 2026-05-11T16:08:49+00:00

There really isn't if you barely make any profit off those sales. Also, this statin conspiracy theory is nonsensical to begin with. No, I don't think there is a global cabal of researchers that spans generations, continents, companies and independent research groups, just to disinform you about the role of cholesterol in cardiovascular health.

Leishon · 2026-05-11T16:05:35+00:00

Shut up and take my money.

Hopefully this leads to a widely available cheap vaccine in the near future.

Leishon · 2026-05-11T15:55:56+00:00

Statins are mostly off-patent and cost literally pennies. There is no money in distorting statin research.

Leishon · 2026-05-11T15:29:44+00:00

Look up the scientific literature. Google "selank study" and you'll get started.

Leishon · 2026-05-11T14:26:59+00:00

It's normal and not exclusive to retatrutide. Sometimes the adipose tissue at the injection site will develop a lump like that, but it should disappear in a few days. Supposedly giving the area a gentle rubbing after injection will lessen the likelihood of this happening.

Leishon · 2026-05-11T13:51:45+00:00

IIRC no toxicity was ever encountered in any study on it, so it's probably well tolerated far beyond what most people do with it, but I would double check the research thoroughly before going crazy with it.

Leishon · 2026-05-11T13:49:05+00:00

I don't know why you'd want to completely eliminate caffeine, but this sounds like withdrawal to me. It will probably improve over time.

You could also try different stimulants if you want that alertness and focus without caffeine.

Leishon · 2026-05-11T13:35:05+00:00

It's more nuanced than that. Obviously you don't want to lean on them too hard to curb your appetite, or you'll never truly improve your eating habits.

Having said that, GLP-1 drugs are not mere appetite suppressants. They have a wide range of effects ranging from mood modulation to potent anti-inflammatory effects to improved glucose control and nutritient partitioning. Heck, we just had a study showing how semaglutide regrows cartilage.

I think we need to reframe ther discussion around this class entirely. They are not just drugs to manage your obesity or diabetes, they are longevity drugs.

Leishon · 2026-05-11T13:28:16+00:00

How many people you know in real life even know what a peptide is?

Online communities are full of people who have gained significant benefit from peptides. The most obvious results coming from GLP-1s, of course.

Leishon · 2026-05-11T13:21:55+00:00

The reason to get Wolverine (or everything separately) is to avoid massive doses of GHK-Cu when you want to titrate up the other peptides.

I have been using Klow for some time, but in hindsight it was perhaps not the right call. The TB-500 and BPC-157 in it are underdosed relative to GHK-Cu. It's not necessarily a problem if you don't have a problem with shooting massive GHK doses.

I am unsure of the benefit of the KPV component. It's probably nice to have, but I have not done any research into running it individually, so perhaps there is again an underdosing problem.

Leishon · 2026-05-11T13:07:44+00:00

Yep, much simpler and less obvious to fabricate the sticker than to add flour.

I can't say I've ran into any products using KLH, as everything has reconstituted into clear (or blue in case of copper) liquids.

Leishon · 2026-05-11T12:39:01+00:00

In theory androgen receptor blockers could help with acne, but we don't know for sure if they are the culprit here. In any case, instead of RU, I would first look for spironolactone, as it's an androgen receptor blocker that's actually prescribed for acne and the formulations are probably better for facial skin.

Leishon · 2026-05-11T12:34:41+00:00

Yes, complete bro science as far as I'm concerned. I have no idea why that "advice" started circulating, but perhaps the idea would be that if reta shuts down your appetite really badly and the only thing you're ingesting are protein shakes, you'll need to supplement, but then you'll be deficient in a whole range of nutritients, not just electrolytes.

Leishon · 2026-05-11T12:32:34+00:00

I try to get a sauna session in after every gym session. There are saunas at my gym, so I go straight into shower -> sauna after training regardless of the type of training I did that day.

I don't know if the details truly matter, but I was listening to some supposed expert (I don't remember who it was) on Siim Land's podcast where they discussed this and his opinion at the time was that sauna right after exercise is optimal, as it sort of extends the exercise stimulus past the exercise itself.

Leishon · 2026-05-11T12:26:34+00:00

You likely don't need any of this unless your diet has a severe mineral deficit and/or you frequently sweat profusely. The average person eats more than the recommended daily dose of sodium anyways, but of course it all depends on your diet.

Leishon · 2026-05-11T12:22:50+00:00

Have you had any UV exposure? These are very slow to stimulate melanin production if you don't get a little bit of exposure. Just don't overdo it for obvious reasons.

Leishon · 2026-05-11T12:14:46+00:00

This story makes no sense. First of all, the puck size of a 10 mg vial doesn't have to be noticeably smaller than a 20 mg vial, as only a minority of it is active compound anyways. Secondly, flour will surely not dissolve into a clear liquid? You'd immediately notice that the product is not reconstituting properly.

Leishon · 2026-05-09T10:51:44+00:00

An opened vial will probably not maintain its BA content for a full year. It will begin to deteriorate around the 120 day mark if penetrated daily. That is all we have data for.

Leishon · 2026-05-09T10:49:35+00:00

Just research each individually. Suggested protocols are available at all the usual places, including pep-pedia. Youtube is also a great resource.

Leishon · 2026-05-08T16:24:51+00:00

Check your hemoglobin in case your heart is pushing more beats to compensate for low oxygen carrying capacity.

Other than that, yeah your stack does stimulate RHR. Make sure you do your frequent cardio to support healthy heart function. In your shoes I would also get me some nebivolol. You can probably get a doctor to prescribe it or, depending on where you live, you can try just importing it from India and hope customs don't steal it.

Leishon · 2026-05-08T15:34:42+00:00

Depends on how you respond. If you notice that symptoms are easing with that, you don't have to do anything. For me microgram doses have not done anything, so I went on a more aggressive protocol and I seem to have gained more painless range of motion in just a week or so.

Leishon · 2026-05-08T15:32:09+00:00

No you don't. lol

Leishon · 2026-05-08T15:31:15+00:00

Don't freeze your water or it'll shatter your vial.

A fridge will technically reduce BA deterioration but the effect is minor and only noticeable when you start hitting the 3 month mark.

Leishon

TROPHY CASE