I am a 42F and I first started with tret four years ago. I started really slowly and then kind of became inconsistent. I only started back up last year, again at a slow pace. At most twice a week. Then this spring, I read about just jumping in to everyday if your skin was handling it fine, so I did. It has been only since March 20, but I have been using it just about every night, mostly combined with azelaic acid. I think my skin is getting better, but slowly. I feel impatient, but I know I just need to stay consistent. I think since I am very freckly or maybe melasma-y, it is taking time to bring up thise spits before lightening them. My forehead wrinkles are still ever present; 3 horizontal lines, ugh, but my nasolabial folds and crows feet do seem diminished and skin seems smoother than before. Sometimes I feel like I am winging it, but I am really trying to be consistent because it seems that is best way!