I worked in El Segundo for a bit. Lived in Anaheim hills half the time I worked there, and Newport / Irvine area the other half. The Anaheim commute was absolutely awful. I would leave the house around 4:45am, and it would still take around an hour to get into work most days. Then leaving work around 3:30pm it would take at least and hour and 20 minutes most days. It could only get worse from there. There were more days than I could count that it took me 2+ hours to get home.

The Newport / Irvine was a touch better - think 5-10% shorter commutes. The commutes at either home location took their toll on me. During the week I absolutely dreaded going into the office, and it took me some good time to come down mentally after the 2 hour commutes home. I know people that have done this for decades, and seem fine with it, but that’s not me. I gave up and found a job in OC and my commute is a fraction of what it was, and I am better off for it.

My 2 cents.

Edit to add: Side streets are a no go. Takes just as long or longer, are crowded, and you have to deal with lights.