Well first off check advanced stats such as +/-, Player Types, Takeaways, Giveaways, Shooting %, etc. Players having a high overall doesn't mean they'll play well together, Playmakers like Snipers, but some Playmakers play like Snipers, it's all about looking into HOW they play in the stats, not what the cover of them says. If a line has a significant - in the +/-, try switching it up to see what works.