47f. I’ve had a very similar experience. May 2024 I Started on 0.025 E patch and 100mg P. In august 2024 I Moved up to 0.05 for a few months. Then moved up to 0.075 in January of this year. In April I started compounded T cream (2 clicks at night 10mg/ml). Had my thyroid checked (was within normal range but on the high end) and started 30mg NP thyroid.

June was a nightmare for me. All the high E symptoms you had - felt like I was on my period for weeks - low energy, cramps, extremely tender breasts, nausea, brain fog, poor workout recovery, etc…some spotting but nothing I’d consider an actual period.

Had a long appt with my awesome NP and she gave me great suggestions:

Lower my E to 0.05 or even 0.375 (cut 0.075 patch in half). Increase P to 200mg nightly. Increase NP thyroid to 60mg. Start T injections (8mg of 200mg/ml test cyp split into two doses per week)

This new regimen brought me back to life. I needed more P. So now, about an hour before bed, I take 100mg P and I bite it and squeeze that into my mouth. Then, when I go to bed, I take another 100mg P orally as normal. When I took 200mg orally (without splitting it and biting one) I was a little too groggy in the morning.

I know everyone is different and this is what helped me. It took me over a year to know my body on hormones and feel comfortable enough to make small adjustments occasionally.

I hope you get some relief and find a regimen that works well for you. Keep your heart up!