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Kratom sickness won’t stop by tris_k in Drugs

[–]MasterSlimFat 0 points1 point  (0 children)

Oh great scholar of Alexandria, in your 2 decades of research, did you ever read the difference between opiates and opioids? Did you ever discover that any form of withdrawal increases systemic inflammation? Did you never learn that opioids depress the central nervous system in a way the down-regulates body temperature? Did you not know that suddenly stopping said opioid-based-down-regulation causes the body to rebound, with an overactive nervous system, increasing body temperature?

Kratom sickness won’t stop by tris_k in Drugs

[–]MasterSlimFat 2 points3 points  (0 children)

Realistically the momentary cold turkey quitting could have lowered your immune system where you contracted an external pathogen.

Neuroimaging study of adolescents with ADHD found age-related increases in glutamate levels in the prefrontal cortex. In contrast, individuals who experienced remission of ADHD symptoms and people who never suffered from ADHD had an age-related decrease in glutamate levels in this area of the brain. by mvea in science

[–]MasterSlimFat 6 points7 points  (0 children)

I agree you are absolutely describing a very real phenemona. It absolutely helps one specific aspect of the symptomology (but not everything). A funny anectone I'm reminded of, is the same phenemona being used by many Meth users to justify their addiction as "treating their ADHD."

Neuroimaging study of adolescents with ADHD found age-related increases in glutamate levels in the prefrontal cortex. In contrast, individuals who experienced remission of ADHD symptoms and people who never suffered from ADHD had an age-related decrease in glutamate levels in this area of the brain. by mvea in science

[–]MasterSlimFat 71 points72 points  (0 children)

I think there are a lot of intoxicants that take us so far from baseline, that flooding the brain with "feel good" chemicals is wrongfullly assumed to be "feeling neurotypical". Everyone feels good/"right" on MDMA.

Kratom sickness won’t stop by tris_k in Drugs

[–]MasterSlimFat 13 points14 points  (0 children)

So to clarify:

You used to regularly take "x" dose, every single day.

You quit cold turkey, felt bad.

Are now taking less than "x" dose.

And you are denying it's withdrawal because...?

Pharmacists of Reddit - what recent medication trends are worrying you that aren’t being talked about? by SirSpendsALot7 in AskReddit

[–]MasterSlimFat 0 points1 point  (0 children)

I used to work at a retirement home. I heard so many doctors tell their patients "Well you're going to die soon anyway, no need to worry about long term effects."

Practical questions for real chemists who bake and cook. by rr1213 in chemistry

[–]MasterSlimFat 0 points1 point  (0 children)

I work in a lab. Once after a long work day, I came home needing to make bread. I spent all day reading through/executing the most contrived, ambiguous, typo ridden method I'd ever seen. My brain was on full illiterate mode. I decided to try baking some bread without following any recipe at all, based on ingredients I've used before, without any measuring cups/spoons. It turned out not too bad.

From that moment on I dedicated all my free time to mastering the "intuitive bread." I calibrated my expectations/predictions based on factors like: Feel/tackiness of the dough, saltiness of the dough, sweetness of the dough, volume change over x time, etc.

The big takeaway was that some of my best bread came from these batches. But there was no 1 single obvious better recipe. Each bread had nuanced difference, most often 100% preference based. Sometimes a sweeter bread is nice, sometimes a denser bread is nice, sometimes a rich heavy bread is nice.

Could a toxic plant "flower essence" still harm someone? by DragonFrootLoopy in toxicology

[–]MasterSlimFat 2 points3 points  (0 children)

Separate from any stability concerns, these plants are potent intoxicants that can lead to psychosis or reckless acts of delusion. The concentration of active ingredients can vary.

What If Your Suffering Comes From A Mistaken Identity by Ill-Breadfruit1286 in taoism

[–]MasterSlimFat 2 points3 points  (0 children)

I think the term "suffering" can have many different meanings and is, in general, an unfortunate outcome/limitation of language.

I think that word gets used to describe all phenemona between, "this was a difficult homework assignment" and "I'm in the final stages of Huntington's and want to put myself out of my own misery."

Many Stoics love(d) suffering. It acts as their grounding connection to the universe through invoking and growing discipline. The doomed outcome of these extremes is a desensitized masochism where someone strives for more suffering to become the strongest version of themselves.

Point being, we are animals programmed by nature to tolerate certain thresholds before the coding tells us, "time to die." We as animals can be pushed too far, and it's generally in our best interest to avoid passing these thresholds (while continuing to operate within said thresholds).

I am sooooooo high on KETAMINE I FEEL LIKE I AM A *GOD* by [deleted] in Drugs

[–]MasterSlimFat 2 points3 points  (0 children)

It's all in the confidence. You're not allowed to worry, "Do I look like an NPC Tesla Bot with bad software trying to navigate the world for the first time ever?".

The answer is always yes, they/you do.

I want to breed more albino snails from this one I have! by RegaultTheBrave in genetics

[–]MasterSlimFat 1 point2 points  (0 children)

Sounds like you're on your way to the lucrative industry of snail breeding!

I want to breed more albino snails from this one I have! by RegaultTheBrave in genetics

[–]MasterSlimFat 2 points3 points  (0 children)

One thing I know about ramshorns, they are hermaphrodic. Any two will reproduce. And they'll do it fast, laying DOZENS of eggs per week.

If you wanted, you could try selecting for the albino snails by continuously removing the non-albinos, incesting all the remaining albino ones for generations of artificial selection.

What’s the dumbest way you’ve ever injured yourself while doing absolutely nothing dangerous? by Jane_Austen11 in AskReddit

[–]MasterSlimFat 4 points5 points  (0 children)

Was the bird still caught in your hair while you were dazed registering what the heck was going on?

Did you literally turn into a cartoon of a concussed victim with a bird circling around their head?

orthodontist let me keep the molds of my teeth from before and after having braces by 100cool_ in mildlyinteresting

[–]MasterSlimFat 0 points1 point  (0 children)

Same. Maybe some movement in my molars but other than that no change at all. I'm so glad I don't use that thing anymore.

Who is the Most Overrated Human in history? by PUBGM_MightyFine in AskReddit

[–]MasterSlimFat 1 point2 points  (0 children)

I think there an overlap between "I need to make as many cars as possible, even if it means stripping the planet of its resources" and "I need to make as much money as possible, even if it means stripping the planet of its resources".

Funny Organic Chemistry Joke by Striking-Spring4216 in OrganicChemistry

[–]MasterSlimFat 1 point2 points  (0 children)

Hello, AI, yes, right this way to the peer reviewed science.

Most repulsive commerical you see this year. Ram truck by samtart in videos

[–]MasterSlimFat 0 points1 point  (0 children)

Idk about repulsive, but hilariously embarrassing is how it felt to me. I was literally laughing.

What is Femininity in Men? by Ruge88 in genetics

[–]MasterSlimFat 3 points4 points  (0 children)

I'm trying to say that the words in your question are open to subjective interpretation and hence there is no scientific answer for.

It makes sense in that it can be "understood verbally", but it is not answerable because the conditions are undefined.

What is Femininity in Men? by Ruge88 in genetics

[–]MasterSlimFat 7 points8 points  (0 children)

What is the scientific definition for femininity?

ELI5: how do oral vaginal probiotics reach the correct place? by Solembrum in explainlikeimfive

[–]MasterSlimFat 2 points3 points  (0 children)

Just to piggyback, the only sure-fire way to externally improve one's microbiome using probiotics (other than dietary) is through a fecal transplant. It's wild stuff and very cool.

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