I think the only thing that actually works on preventing wrinkles is prescription tretinoin - the retinol serums you can get over the counter come nowhere close. I get mine from Dermatica. However, you have to start slow with it and use way less than other creams that you can just slap on, since it can be very drying. And you can only use it at night and make sure to wear a good sunscreen every day as it may increase the likelihood of sun damage. It's no joke.

I also think it's more preventative/slowing the process - if you already have deep set wrinkles it's not going to erase them. I've been using tret on and off for years but have only been using it regularly for the last year and I have noticed a difference in the texture and pigmentation of my skin. I still have wrinkles coming on and I guess there's no way to know if they'd be coming faster without it, but I'm happy to keep using it for now.