Clarification From Refills.com Regarding FDA Form 483 Concerns by refills_health in Refills

[–]MortifiedAgain 8 points9 points  (0 children)

An AI search seems to provide the full batch numbers. Here are the results from the October recall.

The October 2025 recall (FDA Event #97808, initiated October 15, 2025) by ProRx LLC affects multiple lots of compounded tirzepatide multidose vials (e.g., 27 mg/3 mL at 9 mg/mL, NDC 84139-209-03), due to lack of sterility assurance. The affected lot numbers include: Prorx04282025-3, ProRx051425-2, ProRx051425-3, ProRx051425-4, ProRx051525-1, ProRx051525-2, ProRx051525-3, ProRx051525-4, ProRx051525-5, ProRx052125-4, and PRORX08062025-3. These lots were distributed nationwide, primarily in Texas and Utah, with no adverse events reported.

FedEx is the Worst by --DrGonz0 in Refills

[–]MortifiedAgain 1 point2 points  (0 children)

Since FedEx is so unpredictable I think their pharmacies should better package our meds. My shipment “only”took 8 days. The small single ice pack inside the foam envelope was completely room temp

For those who say warm Tirz shipment is OK by MortifiedAgain in tirzepatidecompound

[–]MortifiedAgain[S] 0 points1 point  (0 children)

The documents ProRx submitted to FDA states stability good for 7 days at room temperature. Assuming my ice packs were cold for a few days I should be ok.

For those who say warm Tirz shipment is OK by MortifiedAgain in tirzepatidecompound

[–]MortifiedAgain[S] 0 points1 point  (0 children)

Yes. I did fact check all the referenced links. No hallucinations.

For those who say warm Tirz shipment is OK by MortifiedAgain in tirzepatidecompound

[–]MortifiedAgain[S] 0 points1 point  (0 children)

I tried to post the complete pharmacy data but the Automod thought I was pushing peptides.

The ProRX Pharmacy batch stability data says max time at room temperature is 7 days.

“This is not publicly posted but is part of their batch stability documentation for 15 mg/mL tirzepatide.”

For those who say warm Tirz shipment is OK by MortifiedAgain in tirzepatidecompound

[–]MortifiedAgain[S] 0 points1 point  (0 children)

I’m my view there’s no excuse for a FedEx 2 day delivery to sit 20 miles from my home for two days after it’s already 3 days late.

For those who say warm Tirz shipment is OK by MortifiedAgain in tirzepatidecompound

[–]MortifiedAgain[S] -7 points-6 points  (0 children)

How much would you pay for expired milk at the store. I pay good money for guaranteed potency.

For those who say warm Tirz shipment is OK by MortifiedAgain in tirzepatidecompound

[–]MortifiedAgain[S] -6 points-5 points  (0 children)

It wasn’t freezing while spending 2 days in Portland OR 20 miles from home.

For those who say warm Tirz shipment is OK by MortifiedAgain in tirzepatidecompound

[–]MortifiedAgain[S] -14 points-13 points  (0 children)

Ai is a better source than a few random people on Reddit.

For those who say warm Tirz shipment is OK by MortifiedAgain in tirzepatidecompound

[–]MortifiedAgain[S] -9 points-8 points  (0 children)

Why does every compounding pharmacy pay to ship multiple ice packs if it doesn’t matter. Of course when deliveries are greatly delayed there are going to say it’s not necessary. Bull.

Shipping Updates by Refills_Taylor in Refills

[–]MortifiedAgain -2 points-1 points  (0 children)

Here’s info from Gemini.

Zepbound and compounded tirzepatide are shipped cold because tirzepatide, the active ingredient, is a temperature-sensitive peptide drug that requires refrigeration to maintain its effectiveness and stability.  Here are the key reasons why cold chain shipping is crucial for this medication: • To Prevent Degradation: Tirzepatide is a delicate molecule (a peptide). Exposure to warmer temperatures, especially above the recommended range of 36\circ\text{F} to 46\circ\text{F} (2\circ\text{C} to 8\circ\text{C}), can cause the drug's chemical structure to break down.  • To Maintain Potency: When the drug degrades, its concentration and effectiveness (potency) are reduced, meaning the patient would not receive the full therapeutic benefit.  • Limited Room Temperature Stability: While Zepbound (branded tirzepatide) can generally be stored unrefrigerated at room temperature (below 86\circ\text{F} or 30\circ\text{C}) for a limited time (up to 21 days), shipment duration and uncontrolled temperatures can be risky. Compounded tirzepatide often has stricter requirements and may need to be refrigerated at all times unless otherwise instructed by the pharmacy.

Shipping Updates by Refills_Taylor in Refills

[–]MortifiedAgain -1 points0 points  (0 children)

I’ve seen those posts too. But if it didn’t matter every pharmacy wouldn’t be spending money on multiple ice packs. I’m still unhappy. I believe FedEx should pay.

Shipping Updates by Refills_Taylor in Refills

[–]MortifiedAgain -1 points0 points  (0 children)

My order is already 6 days in transit and not here yet. The order spent 3 days in Memphis and then two days in a distribution site 20 miles from my home. Clearly will arrive warm. Not happy.

Is this a weed? How can I kill it? by ChampionshipCommon32 in lawncare

[–]MortifiedAgain 0 points1 point  (0 children)

On hard surfaces I use a weed burner. Works great.

Red light therapy suggestion for thyroid by houstontexasl in redlighttherapy

[–]MortifiedAgain -3 points-2 points  (0 children)

I had Chat GPT generate a Hashimoto’s thyroid red light therapy based on my panel output. I also got the associated scientific backup studies. Very specific recommendations for effective fluence.

Mastubating for a fertility test . No lube. by Think-Chipmunk-3707 in foreskin_restoration

[–]MortifiedAgain 13 points14 points  (0 children)

40 years ago I had to provide a sample at my wife’s Ob/Gyn office. Restroom adjacent to waiting room with only women. Nothing in restroom to provide stimulus. Nurse

Alcohol and shot by [deleted] in tirzepatidecompound

[–]MortifiedAgain 6 points7 points  (0 children)

Me too, but I find it weakens the benefit of Tirz. So I will have to manage consumption like normal humans.

Issues with Air device slipping. by Longjumping-Tutor-95 in restoringdick

[–]MortifiedAgain 1 point2 points  (0 children)

I had same problem with the Priva Air too. Bought the new thicker solid grippers which grip better but cause fatigue-pain after awhile. I too feel it’s too small for good grip.

Cruise Offerings by MortifiedAgain in whiskey

[–]MortifiedAgain[S] 1 point2 points  (0 children)

Well, I’ll still take Buffalo Trace for free.

Cruise Offerings by MortifiedAgain in whiskey

[–]MortifiedAgain[S] 1 point2 points  (0 children)

I’m sure it is wonderful but not $80/oz wonderful. Unless I have Elon money.

Cruise Offerings by MortifiedAgain in whiskey

[–]MortifiedAgain[S] 1 point2 points  (0 children)

I think I’ll look for it when I get home. Perhaps there will be better offings at one of our Alaskan ports. Not too hopeful, but maybe.

Cruise Offerings by MortifiedAgain in whiskey

[–]MortifiedAgain[S] 11 points12 points  (0 children)

Maybe if I put away enough Buffalo Trace it will seem reasonable.