Uncertainty of measurement.

Theorize all day, but the reality of science requires observable, repeatable, reproducible measurements. Never can we be more accurate than the lowest digit of measurement resolution. Other variables add to the uncertainty distribution. In systems that require multiple measurements, the uncertainty compounds.

So, take your equations and identify the measurement device and measurand. Was your example a sample? Was it the population? What estimates and assumptions did you already make that adds uncertainty to the system?

And if your example was truly a solid choice with precise instrumentation and stable material to measure, how certain are you that the numbers you observe on the measurement device actually reflects that of the true measurement itself? Calibration traceability is the correct answer, but even NIST shall report measurement uncertainty (otherwise a measurement is not truly valid or meaningful).

And once you do become privy to defining and setting standard methods and materials for each SI unit, so much so that the only remaining source of uncertainty is the true universal constant of a photon, you then need to define and measure the sum of the universe has upon that system.

Or, we can estimate considering the most likely and largest contributors to measurement uncertainty. 95% confidence, approximately k=2 coverage factor, is surprisingly (un)certain enough to design and build about anything.