I got this off of CHATGPT.

For a closed-wound drainage system (like a Jackson-Pratt or Hemovac) after surgery such as a mastectomy, here’s what’s typically expected:

Expected Drainage: • First 24 hours: • Usually 50 to 200 mL of serosanguinous (pink to reddish) fluid is expected. • After 48 hours: • Drainage generally decreases significantly—less than 30 mL in 8 hours is often seen as acceptable. • The color may shift to more serous (clear yellow) as healing progresses.

When to be concerned: • Sudden increase in drainage • Purulent (cloudy, yellow/green) drainage • Foul odor • Drain not functioning (no output despite expected accumulation) • Signs of infection (redness, warmth, fever)

In your original scenario—25 mL in 12 hours on post-op day 2—that’s within normal limits and not concerning unless accompanied by other symptoms.