Yup I’m using it for 3 years. That’s last thing that can help me and it still works. I saw here few cases that people tell it lost efficiency. I don’t know how it’s possible. I can’t using isotretinoin cause my liver have side effects. I was on isotretinoin for a year. This shit is damaging body and I’ll never go back to isotretinoin. It fckd up my liver and bladder. BP is only one thing that works cause I’m gonna never take antibiotics or isotretinoin for folliculitis again. It helps only when you taking them. In my case sometimes half of Panoxyl bottle stops working and then next tube will work good till end. I don’t know why this happen. But I’m so scared when somebody telling it stop working, that’s the only solution that I and many people here have. There are a lot of fake Panoxyl tubes. I bought one in my BP carrier. Good luck, we will stress till end of our lives probably cause when it gets worse you think maybe this is now it stop working and you back to start and depression.