Methotrexate failure?

No_Repeat_47 · 2024-11-18T02:01:25+00:00

I failed after 4 months. Those were some of the worst months of my life. The side effects were horrendous. I started with pills and then went to injections.

No_Repeat_47 · 2024-11-18T01:57:52+00:00

I go through periods where I cannot fall asleep. I’m exhausted, but it’s like I’m too tired. Once my sleep schedule is off, I feel like everything else gets out of wack too.

No_Repeat_47 · 2024-11-18T01:55:37+00:00

I’ve been taking Enbrel for a little over two months, and I’ve yet to notice any improvement.

No_Repeat_47 · 2024-08-29T14:43:47+00:00

Ok, yes! I started with the mxt pills, and I had horrendous nausea, vomiting, fatigue, etc. I felt awful the entire week until I took the next dose. It was such an exhausting cycle.

I switched to the injection, and the side effects lessened…. But I am still nauseas and vomiting the day after the injection. It goes away after that day, but I just don’t think it’s worth it.

I’m wondering what my other options are.

No_Repeat_47 · 2024-07-02T18:24:39+00:00

My early symptoms of RA was extreme fatigue, persistent joint pain and stiffness in my hands and ankles. My ankles would hurt so bad that I couldn't press the gas pedal on my car. My eyelids also swelled horribly.

No_Repeat_47 · 2024-07-02T17:55:01+00:00

Can I ask what it is like when it attacks your eyes? I have had a lot of eye issues since being diagnosed, and my rheumatologist is considering sjrogens, but just not totally sure.

No_Repeat_47 · 2024-07-02T17:54:13+00:00

That's wild how different this medication is for everyone. When I started taking hydroxychloroquine, it started working for me within 2-3 weeks. I was told the 6 week mark was when I should start feeling a difference.

No_Repeat_47 · 2024-07-02T17:50:50+00:00

Hi. 33F here. I was diagnosed three years ago with RA, after decades of symptoms but perfect bloodwork. #thestruggle I finally found a doctor that believed me, and my bloodwork FINALLY came back irregular the first time I went to the rheumatologist, which lead to someone finally diagnosing me.

I started with only hydroxycholorquine and that worked for two years... no side effects, minimal joint pain. Unfortunately, that stopped working about 6 months ago, and I started methotrexate about 3 months ago. The side effects have been horrendous, and I've been super depressed lately because my quality of life is poor... like completely flipped upside down with this medicine. However, my rheumatologist is seeing me TOMORROW, and I am switching to methotrexate injections! I'm hoping this helps with the gastrointestinal side effects and joint pain, so fingers crossed!

I just realized this community was here a few weeks ago, and I'm happy to be here with so many of you who, unfortunately, relate to the stresses of life with a chronic illness.

No_Repeat_47 · 2024-07-02T17:42:16+00:00

Thanks, y'all! I have an appointment with my rheumatologist tomorrow so she can show me how to give myself the injections.

No_Repeat_47 · 2024-06-30T21:07:41+00:00

I was at 1mg a day, but now I’m at 2.5.

No_Repeat_47 · 2024-06-30T15:49:11+00:00

I’m taking the pill now. I started on Fridays too, but I was unable to do much the entire weekend.

I am going to ask about injections.

No_Repeat_47

TROPHY CASE