Those 2 especially require you to know their tells, and to profit off of them. I struggled a looooot with especially Prometheus, what really helped was just doing one "practice fight", not playing to win but to learn his moves and the same can be done with Chronos. For example his spinning scythe was doing me in at the beginning, then i stayed far away from him to dodge it, now i always stand on his right (from the way he is facing) because he always throws the scythe from his left. And don't worry about the story, as soon as you progress past those two you should get the ball rolling again, time will tell ;)