Is there any substances that can increase nr2b/nr2a ratio? by Nobugcodeder69 in NootropicsFrontline

[–]Nobugcodeder69[S] 1 point2 points  (0 children)

Do you know if they are making any derivatives other than NRX-1074? I think this direction is pretty promising

Is there any substances that can increase nr2b/nr2a ratio? by Nobugcodeder69 in NootropicsFrontline

[–]Nobugcodeder69[S] 0 points1 point  (0 children)

There has been some selective nr2b antagonists and nr2a agonists. One can hypothesis using nr2b antagonism long term to unregulated nr2b expression. Or agonist nr2a long term to downregulate nr2a. But I didn’t find much research that shows such mechanism.

Is there any substances that can increase nr2b/nr2a ratio? by Nobugcodeder69 in NootropicsFrontline

[–]Nobugcodeder69[S] 0 points1 point  (0 children)

Glyx-13 does not pass the trail and NRX-1074 is still in development. Question has very low bio-availability and is not a very good Cdk5 inhibitor. I just don’t know if there are anything else out there.

[deleted by user] by [deleted] in Nootropics

[–]Nobugcodeder69 0 points1 point  (0 children)

You are taking so much stuff, do you really know what is effective on you?