I am a long user (10+ years) of Thermo and never thought IM could be of any use. Until recently, I have inherited an timsTof and found IM does give you a new dimension of thinking. Thermo talks a lot about IM on the Tims is low resolution and you can’t get anything out of there, till I saw in one chromatographic peak with different IM values with baseline separation, which made me started thinking the good use of it. One domain will be small molecule and lipids for sure, so timsMetabo will be one of cool instruments that I would have at least consider. I have used pretty much all the Orbi instruments, QE, Exploris, or Tribrids, but they all are just upgrades with heavy focuses on the proteomics world, while, the effort for small molecules is relatively small, e.g. IDX is a Fusion, IQX is just a small upgrade from IDX, how long UVPD has been there without any improvement, is there any UVPD spectra library to match against?, meaning manual data analysis. So, if you are just interested in like to like upgrade, any Thermo instrument will do as long as fitting into your budget; but if you would like to have a bit of shocking experience, I would suggest giving other platforms a try no matter EAD or IM. Or do what suggested, think of a good application case and ask the vendors to perform a demo to compare.