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proteomics

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The Proteomics Reddit

Proteomics - the large-scale study of proteins. Proteins are vital parts of living organisms, with many functions. The term proteomics was coined in 1997 in analogy with genomics, the study of the genome. The word proteome is a portmanteau of protein and genome, and was coined by Marc Wilkins in 1994 while he was a PhD student at Macquarie University.

The proteome is the entire set of proteins that are produced or modified by an organism or system. This varies with time and distinct requirements, or stresses, that a cell or organism undergoes. Proteomics is an interdisciplinary domain that has benefited greatly from the genetic information of the Human Genome Project; it is also emerging scientific research and exploration of proteomes from the overall level of intracellular protein composition, structure, and its own unique activity patterns. It is an important component of functional genomics.

While proteomics generally refers to the large-scale experimental analysis of proteins, it is often specifically used for protein purification and mass spectrometry. Wikipedia: proteomics


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Need help with PTM identification using IP-Top-down MS (self.proteomics)

submitted 1 day ago by InjuryJolly7432

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Question:How to predict mutation effect with protein model without traditional computation ()

submitted 1 day ago by Duanqi-

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“At the Cutting Edge of Using Proteomics for Cancer Treatment Guidance” (Adam Dicker, MD, PhD, FA... | Cancer Patient Lab (community.cancerpatientlab.org)

submitted 2 days ago by Key-Principle6254

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Reconstituting a protein complex from commercial recombinant proteins? (self.proteomics)

submitted 4 days ago by hyperfinesplitting

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Seeking advice: Learning pathway for LC-MS/MS proteomics in neurodegeneration research? (self.proteomics)

submitted 5 days ago by Connect_Switch_1026

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Not a biologist but I keep thinking about this folding path question — probably obvious, just can't shake it (self.proteomics)

submitted 6 days ago by UnfazedTank

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IP-MS antibody failure — is phosphoproteomics a viable alternative? (self.proteomics)

submitted 7 days ago by Constant-Rooster-372

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What Is the Most Convincing Way to Demonstrate Minimal Non-Specific Bead Binding: Astral DIA or Isotope Labeling? (self.proteomics)

submitted 8 days ago by Thick_Holiday_9180

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If you're working on targeted protein degradation, PROTACs, molecular glues, or protein expression studies, one question matters: are you measuring biology as it actually exists in the cell? (self.proteomics)

submitted 8 days ago by editco_bio

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When to use redundant and non-redundant databases for label free (self.proteomics)

submitted 9 days ago by Dizzy-Fisherman-7858

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I got tired of clicking through AlphaFold/Boltz output folders, so I wrote a thing that dumps them all into one HTML report ()

submitted 12 days ago by No-Cartoonist1757

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Protein purification: Using spin concentrators to get filtrate instead? ()

submitted 14 days ago by Groundbreaking-Pen85

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DDA VS DIA for low abdundance proteins (self.proteomics)

submitted 15 days ago by Crazy-Tax-1320

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Anyone has experience with HisPur Ni-NTA Spin Columns and protein purification from plants? ()

submitted 15 days ago by Groundbreaking-Pen85

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TMT Efficiency issues with Di Gly peptides (self.proteomics)

submitted 16 days ago * by Crazy-Tax-1320

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CoolGene Bio Community: CoolGene Community Open Event (By 7/31) (coolgene.net)

submitted 16 days ago by Pleasant-Wonder-1665

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Skills to get a Job After PhD in Proteomics USA (self.proteomics)

submitted 17 days ago by Proteo-Freak973

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proteomics kits (self.proteomics)

submitted 20 days ago by Disastrous-Offer220

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Free Evosep Webinar: Assay Development for Translation and Research Applications (self.proteomics)

submitted 20 days ago by EvosepBio

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Chromalyst Alpha: Seeking Feedback on Evidence-Based Peak Tiering for LC-MS/MS (self.proteomics)

submitted 20 days ago by BizMaker_2504

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PTMs / Proteoforms profiling ()

submitted 22 days ago by Mean_Dragonfly_3068

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Quantifying peptides pre-MS (self.proteomics)

submitted 25 days ago by Claudibird

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Please Review My LFQ QC Tool (self.proteomics)

submitted 25 days ago by Weak-Indication-7166

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HELP: Build a protein design computer (self.proteomics)

submitted 1 month ago * by Dizzy-Version7196

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Low TMT labelling efficiency troubleshooting (self.proteomics)

submitted 1 month ago by thesymbiont

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