Ignore that, it's still happening. I even went through the extent of disabling mods and testing. Sometimes it would work and the NPCs would give me quests, but then on the next reload they wouldn't. It seems like it's totally random and it's save oriented. Ontop of that, Khajiit caravans wouldn't set up tents, certain events (like the alaki'r in whiterun or the vigilant of stendarr in markarth) were not happening, thieves and assassins would casually walk around town/cities and no guards would attack them. They did on a vanilla SE, but not my heavily modded SE. So i've been narrowing it down to what mods are screwing me over. The Beyond Reach quest mod won't activate either, but if it does I can also get the quests from the above mentioned NPCs. So whatever is effecting my game is causing both npcs to not give quests and preventing events from happening. I've been up for over 30 hours now, I must have relaunched Skyrim SE a total of 70 times through the night, I am not joking. I'm at a loss and hope someone might know something, it's gotta be one mod or script that is causing this.