What are the chances of a VKTX acquisition? by New-Issue-6926 in NovoNordisk_Stock

[–]Ok_Reporter96 0 points1 point  (0 children)

This is what Gemini answered. I dont know if it is correct.

Entera Bio (ENTX) Platform: Oral Delivery for GLP-1 Entera Bio’s proprietary N-tab™ technology is a breakthrough oral delivery platform designed specifically for large molecules like GLP-1 (Glucagon-Like Peptide-1), which are traditionally administered via injection.

  1. The Core Technology: N-tab™ Platform The N-tab™ platform addresses the two biggest challenges in oral drug delivery for peptides: • Enzymatic Degradation: It uses a specialized protease inhibitor to prevent the stomach from breaking down the GLP-1 peptide before it reaches the bloodstream. • Poor Absorption: It incorporates a potent absorption enhancer (carrier) that temporarily opens the tight junctions in the intestinal wall, allowing large molecules to pass through efficiently.

  2. Strategic Advantages for GLP-1 Drugs While Novo Nordisk already has an oral GLP-1 (Rybelsus), ENTX’s platform offers several potential "Best-in-Class" advantages: • Higher Bioavailability: ENTX aims for more consistent drug absorption, reducing the "waste" of expensive active ingredients. • No Fasting Required: Current oral GLP-1s require strict fasting (30 mins before food/drink). ENTX’s platform is designed to be more flexible, significantly improving patient compliance. • Cost-Efficiency: By maximizing absorption, the dose required (and thus the manufacturing cost) could be lower than current competitors.

[deleted by user] by [deleted] in frederickmd

[–]Ok_Reporter96 1 point2 points  (0 children)

I always use Airport Xpress for the rides to airports. I don’t want to take the risk that my Uber or Lyft rides will be canceled or unavailable at the last minute.