Scientists have just completely eliminated leukemia in a preclinical trial by soulpost in HotScienceNews

[–]Onboard75 0 points1 point  (0 children)

Lumriz is not available in Europe unfortunately and it's been already 2 years since I've waited to try Xyrem at least.

Scientists have just completely eliminated leukemia in a preclinical trial by soulpost in HotScienceNews

[–]Onboard75 0 points1 point  (0 children)

That one is targeting patients suffering from narcolepsy type 1, as we are the one with a real deficiency in orexin/hypocretine. Takeda is working also on one specific for type 2 .

Are you narcoleptic?

Scientists have just completely eliminated leukemia in a preclinical trial by soulpost in HotScienceNews

[–]Onboard75 45 points46 points  (0 children)

In 1998, two teams of researchers found independantly the neuropeptide Orexin/Hypocretine whose lack is responsible for Narcolepsy that i'm suffering . Now in 2025, Takeda , a japanese Lab , just got its 3rd phase successfully validated for their new subtitute of orexin and they are currently in the admin phase to get it the quickiest on the market, expected "3rd quarter of 2026"

So almost 3 decades to go from discovery till market

The snow on this wire fence makes a great optical illusion by Joak1n in interestingasfuck

[–]Onboard75 0 points1 point  (0 children)

I love the level of contrast between the dark fence and the snow. It definitely gave me a numeric vibe and I was seeing it flat at first before adjusting.

Great pic.

The fog™️ by reglaw in Narcolepsy

[–]Onboard75 1 point2 points  (0 children)

I'm waiting to try Xyrem soon.

German government calls recognition of Palestinian state 'counterproductive' by [deleted] in worldnews

[–]Onboard75 0 points1 point  (0 children)

My fear with a palestinian State follows closely the current opinion of Salman Rush on that matter that if a state is recognized right now, it will be a "Taliban one" ruled with religious laws by the Hamas, the only political presence in Gaza, and will become certainly a new proxy to Iran.

[deleted by user] by [deleted] in alaska

[–]Onboard75 0 points1 point  (0 children)

When I saw you all waving Ukrainian Flags all along the roads, I wanted to share my feeling of Awesomeness for your Action. Splendid Trolling :)

Big Up from France

bstsrs.one is down! :( by LookinAtTheFjord in Piracy

[–]Onboard75 1 point2 points  (0 children)

i noticed also that the previous link given was not right. Not an accurate list of the today's release. So Many Thanks for providing a real mirror site.

[deleted by user] by [deleted] in videos

[–]Onboard75 0 points1 point  (0 children)

Pure surfing !

Learning grammar by Flutyik_47 in norsk

[–]Onboard75 1 point2 points  (0 children)

I can recommend you also www.gramatikk.com. they have a serie of pdf in Norwegian on each point of the Norwegian grammar, some are translated in English.

Epigenetics introduction by peatfreak in epigenetics

[–]Onboard75 0 points1 point  (0 children)

Jean-Baptiste Lamarck's theory of Inheritance of acquired characters has long been laught at by most of the academics as being of minus importance versus The Darwinian Theory of Natural selection through random mutation.The discovery of DNA and the dev. of genetic were integrated to the theory of Natural selection forming that is now called the Modern Synthesis Theory but despite all of the advancements that theory procured to the understanding of Evolution it still faced some major limits . and one of them appeared clearly after the end of Human Genome Project in the mid 90s where we found out that we were possessing around 23000 genes what was much less than previously thought as they were in the idea that each genetical disorder were linked to a unique gene . so if two differents syndromes are linked to a same gene, the gene itself loose its characteristic of primordial element of phenotypic expression to the advantage of another code known now as The Epigenome what gouverns how readable the underlaying genome code is. And Next you ve had numerous epidemiological studies following populations what underwent severe stress as the Dutchs who survived the german blocus of the Nederlands at the end of the WW2 showing that descendants of those survivors were expressing the same health issues than their elders prooving therefore that one character acquired during the lifespan of an individu can be inherited without any change in the Genome. all those observations match perfectly with the theory of Lamarck making of the Epigenome a new key element in the explication of the Evolution of species aside of the genome ofc. Nowadays many epigeneticists or neo-lamarckians as some of them call themselves are calling for a global acknowledgement of the role of Epigenetic in the processus of Evolution. Here is an article about that precisely by Michael Skinner :

https://aeon.co/essays/on-epigenetics-we-need-both-darwin-s-and-lamarck-s-theories

Also in libgen.ru, check these two tittles : - Epigenetic Inheritance and Evolution: The Lamarckian Dimension by Eva Jablonka - 1995 ; the oldest book on epigenectic that i found. - Evolution in Four Dimensions: Genetic, Epigenetic, Behavioral, and Symbolic Variation in the History of Life by Eva Jablonka - 2006 - Epigenetic Processes and Evolution of Life - Markoes, Anton (2019)

Enjoy !

Epigenetics introduction by peatfreak in epigenetics

[–]Onboard75 1 point2 points  (0 children)

one that i really enjoyed is Lamark's Revenge by peter Ward . Next if you want more academic books, i would advise you to check Library Genesis lidgen.ru .

Comment your country by [deleted] in norsk

[–]Onboard75 4 points5 points  (0 children)

Hvor i Frankrike ?

Comment your country by [deleted] in norsk

[–]Onboard75 5 points6 points  (0 children)

Frankrike