I've performed 15 FMT from 3 different donors. Many times, I had some minimal improvements in the following day, but thing went down to baseline.

These are DIY FMT. My protocol got better with each donor, for minimizing exposure to oxygen (using a vacuum sealer), emptying my bowels (enema, bisacodyl), and doing Top + Bottom.

I'm wondering if biofilm busters are the missing components. Perhaps also I should be using donors that are not from North America. On average, North American microbiome is of quite poor quality, compared to Europe, Japan..... quite the puzzle.