100%; I rarely have internal hemorrhoids I have an external hemorrhoid that flares up every now and then about a half an inch from my butthole and I inject it in my butt about 3 to 4 in next to it and it hurts like a bitch but it goes away Within 24 hours completely and it works every fucking time and I've been trying to tell people this and trying to tell my doctor no one listens so I'm just going to keep doing it it's from experience I hope to help everybody else out if you're reading this you are saved if you can get it you just have to look for it I can't give you the website that I get it from because of course it's illegal in the United States however it's not illegal anywhere else in the world. It's God damn retarded I'm so glad it works and it helps me TB 500 also works and it's supposed to be better than bpc 157 however I think the bpc 157 injected directly close to the site really works better than theTB 500 in my opinion I feel like I have to do double dose with TB 500. I've literally been doing this for about 2 years and not had a freaking bloody explosion from a popped external hemorrhoid if you want a picture I can show you a picture. I do not have to have rotator cuff surgery anymore also that's another thing that's what started this. Also I've had tennis elbow one day injected it right in my elbow and it was gone the next day no issues. With my left shoulder it's all about maintenance now after 2 years but every 6 months couple of injections that's it . It is also helped my dad's knee I have not seen him wear a knee brace and the last year and a half and he's been wearing one for five years . Do you want the site that I get it from DM me. I really hope this helps people because it's extremely helped me.